2-(4-(4-Bromophenyl)-2-(pyridin-3-yl)thiazol-5-yl)acetic acid CAS 554423-29-9
| CAS No. | 554423-29-9 |
| Molecular Formula | C16H11BrN2O2S |
| Molecular Weight | 375.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(4-(4-Bromophenyl)-2-(pyridin-3-yl)thiazol-5-yl)acetic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(4-(4-Bromophenyl)-2-(pyridin-3-yl)thiazol-5-yl)acetic acid (CAS 554423-29-9), a certified reference material (molecular formula C16H11BrN2O2S, MW 375.24 g/mol) for analytical method development and quality control.
2-(4-(4-Bromophenyl)-2-(pyridin-3-yl)thiazol-5-yl)acetic acid (C16H11BrN2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-(4-Bromophenyl)-2-(pyridin-3-yl)thiazol-5-yl)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H11BrN2O2S |
| Molecular Weight | 375.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Bromophenyl Standards
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- N4-(4-Bromophenyl)-N2-(2-(2-hydroxyethoxy)ethyl)-L-asparagine (CAS 1098637-73-0)
- 2-(2-Bromophenyl)-1H-imidazo[4,5-b]phenazine (CAS 114991-78-5)
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- Benzyl 4-(4-bromophenyl)piperazine-1-carboxylate (CAS 1150271-33-2)
- 1-(4-Bromophenyl)-7,8-dimethoxy-4-methyl-4,5-dihydro-3H-benzo[d][1,2]diazepine (CAS 1564270-44-5)
Recommended Standards
- 1,1,1-Trifluoro-N-(4-fluorophenyl)-N-((trifluoromethyl)sulfonyl)methanesulfonamide (CAS 36035-54-8)
- 2-[2-(3-Bromothiophen-2-yl)-2-oxoethyl]-3-methyl-1,4-dihydronaphthalene-1,4-dione (CAS 303148-58-5)
- 2-Bromo-N-(4,5-dimethylisoxazol-3-yl)-N-(methoxymethyl)benzenesulfonamide (CAS 415697-57-3)
- Ceritinib Impurity 10 (CAS CATO-C4X-1048910)
- 6-Amino-1-(3-hydroxypropyl)-3,4-dihydroquinazolin-2(1h)-one (CAS 1258652-58-2)
- 4-Bromo-6-(2,2,2-trifluoroethoxy)pyrimidine (CAS 1602475-97-7)
- 5-(4-Cyclopropanecarbonylpiperazin-1-yl)pyridin-2-amine (CAS 1154964-61-0)
- 2,2'-(Ethane-1,2-diylbis(oxy))diphenol (CAS 20115-81-5)
- 2-Fluoro-3-(trifluoromethyl)benzyl Bromide (CAS 184970-25-0)
- 1-(3-Methylthiophen-2-yl)-1-(1H-pyrrol-2-yl)ethan-1-ol (CAS 944646-20-2)
- 1,6-Anhydro-beta-D-mannopyranose (CAS 14168-65-1)
- 1-(Tetrahydrothiophen-3-yl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1707594-44-2)
- L-(-)-Mannose (CAS 10030-80-5)
- Peptide 437 (CAS CATO-CPTD788437)
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