2-(Hydroxymethyl)-3-methylbenzofuran CAS 55581-62-9
| CAS No. | 55581-62-9 |
| Molecular Formula | C10H10O2 |
| Molecular Weight | 162.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(Hydroxymethyl)-3-methylbenzofuran meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-(Hydroxymethyl)-3-methylbenzofuran (CAS 55581-62-9), molecular formula C10H10O2 and molecular weight 162.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(Hydroxymethyl)-3-methylbenzofuran (C10H10O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H10O2 |
| Molecular Weight | 162.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
Related Hydroxymethyl Standards
- 2-(Hydroxymethyl)-4,6-dimethylnicotinonitrile (CAS 1383468-71-0)
- 2-(Hydroxymethyl)-1-phenylprop-2-en-1-one (CAS 15121-79-6)
- 2-(Hydroxymethyl)-4-methylbenzimidazole (CAS 191794-20-4)
- 6-(Hydroxymethyl)-2,3-dihydro-1H-inden-1-one (CAS 193819-51-1)
- 5-(Hydroxymethyl)-2,3-dihydro-1H-inden-1-one (CAS 760995-53-7)
- 1,3-Bis(hydroxymethyl)imidazolidine-2-thione (CAS 15534-95-9)
- 4-(Hydroxymethyl)-1-methylphosphinane 1-oxide (CAS 2713153-71-8)
- 3-Ethyl-3-(hydroxymethyl)pentane-2,4-diol (CAS 1823903-94-1)
Recommended Standards
- 2-(Hydrazinylmethyl)-1H-benzo[d]imidazole (CAS 99303-41-0)
- 2-(Imidazo[1,2-a]pyrimidin-2-yl)ethan-1-amine (CAS 936940-74-8)
- 2-(Benzofuran-4-yl)ethanol (CAS 943906-70-5)
- 2-(Imidazo[1,2-a]pyrimidin-3-yl)ethan-1-amine (CAS 944896-88-2)
- 2-(Carboxy(hydroxy)methyl)-5-fluorobenzo[d]oxazole (CAS 1804080-07-6)
- 1-(4-Piperidinyl)-1-ethanol hydrochloride (CAS 945374-68-5)
- (5-(Benzo[d][1,3]dioxol-5-yl)isoxazol-3-yl)methanamine hydrochloride (CAS 1351648-34-4)
- Methyl 2-(2-(4-(benzyloxy)phenoxy)acetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 333766-48-6)
- N-(3-Methoxybenzyl)-1-propyl-1H-pyrazol-3-amine hydrochloride (CAS 1856041-57-0)
- 3-Chloro-2-((diphenylmethylene)amino)pyridin-4(1H)-one (CAS 1174046-74-2)
- 5-Methyl-4-nitro-3-(perfluoropropyl)-1H-pyrazole (CAS 82633-69-0)
- trans-4-azidocyclohexanol (CAS 1380214-98-1)
- Docetaxel Impurity 90 (CAS CATO-C4X-161990)
- Cholecystokinin Octapeptide (desulfated) (CAS 25679-24-7)
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