1-(Naphthalen-2-ylsulfonyl)-4-(5-(trifluoromethyl)pyridin-2-yl)piperazine CAS 556010-07-2
| CAS No. | 556010-07-2 |
| Molecular Formula | C20H18F3N3O2S |
| Molecular Weight | 421.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-(Naphthalen-2-ylsulfonyl)-4-(5-(trifluoromethyl)pyridin-2-yl)piperazine (CAS 556010-07-2), a certified reference material (molecular formula C20H18F3N3O2S, MW 421.44 g/mol) for analytical method development and quality control.
The molecular framework of 1-(Naphthalen-2-ylsulfonyl)-4-(5-(trifluoromethyl)pyridin-2-yl)piperazine (C20H18F3N3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(Naphthalen-2-ylsulfonyl)-4-(5-(trifluoromethyl)pyridin-2-yl)piperazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H18F3N3O2S |
| Molecular Weight | 421.44 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Naphthalen Standards
- Bis(4-(naphthalen-2-yl)phenyl)amine (CAS 1446448-94-7)
- 4-(Naphthalen-1-yl)-N-(4-(naphthalen-2-yl)phenyl)aniline (CAS 1446448-95-8)
- N-(4-(naphthalen-1-yl)phenyl)-4-phenylnaphthalen-1-amine (CAS 949462-20-8)
- 1-(Naphthalen-2-yl)-2-((5-(4-pentylcyclohexyl)-1,3,4-oxadiazol-2-yl)thio)ethan-1-one (CAS 860611-00-3)
- (E)-4-(2-(naphthalen-1-yl)vinyl)-8-(trifluoromethoxy)-2,3-dihydrothieno[3,2-c]quinoline (CAS 866133-45-1)
- 9-(Naphthalen-2-yl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9H-carbazole (CAS 1493715-28-8)
- 6-(Naphthalen-2-yl)-3-(4-pentylcyclohexyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine (CAS 860611-02-5)
- (10-(4-(Naphthalen-2-yl)phenyl)anthracen-9-yl)boronic acid (CAS 853945-48-9)
Recommended Standards
- (S)-Benzyl 2-(((benzyloxy)carbonyl)amino)-3-(3,4-dihydroxyphenyl)propanoate (CAS 37169-42-9)
- 2-Methyl-5-(6-(4-(2-(trifluoromethyl)phenoxy)piperidin-1-yl)pyridazin-3-yl)-1,3,4-thiadiazole (CAS 921605-87-0)
- (2-(3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)thiazol-4-yl)(4-phenylpiperazin-1-yl)methanone (CAS 955976-76-8)
- 3-(((9H-Fluoren-9-yl)methoxy)carbonyl)-5-(methoxycarbonyl)-3-azabicyclo[3.1.1]heptane-1-carboxylic acid (CAS 2580228-29-9)
- 1-Ethyl-6-methyl-5-nitropyridin-2(1H)-one (CAS 1624262-14-1)
- 2'-Phenylspiro[indoline-3,3'-pyrrolidin]-2-one (CAS 2756-04-9)
- 3,4-Dimethylbenzonitrile (CAS 22884-95-3)
- 4-Bromo-5-nitropyridin-2-amine (CAS 84487-11-6)
- 9-(1,6-Dimethyl-1,2,3,4-tetrahydroquinolin-4-yl)-9H-carbazole (CAS 167288-54-2)
- 4,6-Dichloro-2-(trifluoromethyl)-1H-imidazo[4,5-c]pyridine (CAS 1422701-22-1)
- Dabigatran Impurity 149 (CAS CATO-C4X-1089149)
- Dimethyl adamantane-1,3-dicarboxylate (CAS 1459-95-6)
- (Z)-({4-[(4-fluorophenyl)methoxy]-3-methoxyphenyl}methylidene)(methyl)oxidoazanium (CAS 321432-07-9)
- Tau Peptide (306-336) (Repeat 3 Domain) trifluoroacetate salt (CAS 330456-26-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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