3-[3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]propanoic acid CAS 556016-22-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-[3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]propanoic acid.

CATO supplies 3-[3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]propanoic acid (CAS 556016-22-9), a certified reference material (molecular formula C17H13FN2O3, MW 312.30 g/mol) for analytical method development and quality control.

Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 3-[3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]propanoic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 312.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-[3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]propanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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