2-Methyl-6-(trimethylsilyl)phenyl trifluoromethanesulfonate CAS 556812-44-3
| CAS No. | 556812-44-3 |
| Molecular Formula | C11H15F3O3SSi |
| Molecular Weight | 312.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Methyl-6-(trimethylsilyl)phenyl trifluoromethanesulfonate (CAS 556812-44-3) is a high-purity analytical reference standard with the molecular formula C11H15F3O3SSi and a molecular weight of 312.38 g/mol.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 2-Methyl-6-(trimethylsilyl)phenyl trifluoromethanesulfonate is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 312.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H15F3O3SSi |
| Molecular Weight | 312.38 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 4-Methyl-2-(trimethylsilyl)phenyl trifluoromethanesulfonate (CAS 262373-15-9)
- 2,4-Bis((trimethylsilyl)oxy)furo[3,4-d]pyrimidin-7(5H)-one (CAS 89000-18-0)
- N-(9-(Trimethylsilyl)-9H-purin-6-yl)benzamide (CAS 60855-35-8)
- Bis(4-(trimethylsilyl)phenyl)amine (CAS 915406-65-4)
- 2-[(trimethylsilyl)oxy]-n,n-bis{2-[(trimethylsilyl)oxy]ethyl}ethanamine 21354-23-4 AR-1D6358 (CAS 21354-23-4)
- 2-{2-[4-(trimethylsilyl)-1H-1,2,3-triazol-1-yl]ethyl}-2,3-dihydro-1H-isoindole-1,3-dione (CAS 1461706-40-0)
- Tris(trimethylsilyl) Phosphate (CAS 10497-05-9)
- 1,1-Bis(trimethylsilyl)-3-(3-fluorophenyl)-2-thiourea (CAS 71457-02-8)
Recommended Standards
- 2-Fluoro-4-(4-methylpiperazinomethyl) benzophenone (CAS 898783-89-6)
- 2'-Phenylspiro[thiochromane-3,5'-[1,3]dioxan]-4-one (CAS 338755-84-3)
- 2-Fluoro-3-(4-methylpiperazinomethyl) benzophenone (CAS 898788-98-2)
- 3-(Benzofuran-2-ylthio)propyl benzoate (CAS 62688-13-5)
- 5-Bromo-7-fluoro-1H-indole-3-carbaldehyde (CAS 1227599-16-7)
- 2-Bromo-5-fluorobenzamide, 97% (CAS 1006-34-4)
- 2-(Aminomethyl)-3-chloro-5-(difluoromethyl)-4-nitropyridine (CAS 1804378-99-1)
- 4-(trifluoromethyl)-1,3-thiazole (CAS 101048-75-3)
- N-(1-(2-Methoxyethyl)piperidin-4-yl)-1-naphthamide (CAS 1421514-18-2)
- ethyl 1H-imidazo[4,5-c]pyridine-4-carboxylate (CAS 2107491-94-9)
- N,N-dimethyl-3-(4-((methylamino)methyl)phenoxy)propan-1-amine (CAS 910037-04-6)
- Ethyl 4,5-dimethyl-2-[(phenoxycarbonyl)amino]thiophene-3-carboxylate (CAS 1031130-84-3)
- 2-Methyl-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrochloride (CAS 63937-92-8)
- Semaglutide Impurity 8 (CAS CATO-C4X-22268)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com