Olopatadine Impurity 37 CAS 55689-64-0
| CAS No. | 55689-64-0 |
| Molecular Formula | C17H14O4 |
| Molecular Weight | 282.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Olopatadine Impurity 37.
CATO supplies Olopatadine Impurity 37 (CAS 55689-64-0), a pharmacopoeial impurity reference standard (molecular formula C17H14O4, MW 282.29 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Olopatadine Impurity 37 (C17H14O4) contains a flavonoid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 282.29 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H14O4 |
| Molecular Weight | 282.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
Related Olopatadine Standards
- Olopatadine Impurity 25 (CAS 88630-37-9)
- Olopatadine Impurity 28 (CAS 55453-89-9)
- Olopatadine Impurity 20 (CAS 962-95-8)
- Olopatadine lmpurity 58 (CAS CATO-C4X-171858)
- Olopatadine Impurity 66 (CAS CATO-C4X-171866)
- Olopatadine Impurity 18 (CAS 55453-90-2)
- Olopatadine USP Related Compound C (CAS 55453-87-7)
- Olopatadine Impurity 26 (CAS 55690-18-1)
Recommended Standards
- Gabapentin Impurity 37 (CAS 79371-39-4)
- Paliperidone Impurity 96 (CAS CATO-C4X-172496)
- Piracetam impurity 39 (CAS CATO-C4X-123539)
- Phenytoin Impurity 21 (CAS CATO-C4X-186421)
- Cetirizine EP Impurity G (CAS 109806-71-5)
- Phosphoramidite Impurity 27 (CAS CATO-C4X-288627)
- N-Nitroso Fluoxetine EP Impurity A (CAS 2659259-65-9)
- 3-((Pyridin-4-ylmethyl)amino)pyrrolidine-2,5-dione (CAS 1189133-39-8)
- 4-Hydroxy-4-(4-methoxyphenyl)butanoic acid (CAS 63639-61-2)
- 7-Fluoro-5-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS 1449581-03-6)
- Ibuprofen Impurity 145 (CAS 69363-33-3)
- Imatinib Impurity 84 (CAS CATO-C4X-106884)
- 2-(Phenylamino)pyrimidine-5-carbaldehyde (CAS 108002-87-5)
- 3X Flag Peptide trifluoroacetate salt (CAS 402750-12-3)
Why CATO?
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