1-Methyl-6-thioguanosine CAS 55727-08-7
| CAS No. | 55727-08-7 |
| Molecular Formula | C11H18N4O4S |
| Molecular Weight | 302.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Methyl-6-thioguanosine.
1-Methyl-6-thioguanosine (CAS 55727-08-7) is a high-purity analytical reference standard with the molecular formula C11H18N4O4S and a molecular weight of 302.35 g/mol.
Based on its molecular formula C11H18N4O4S, 1-Methyl-6-thioguanosine contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 302.35 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-Methyl-6-thioguanosine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H18N4O4S |
| Molecular Weight | 302.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 8-Oxo-7-thioguanosine (CAS 122970-43-8)
- 8-Thioguanosine (CAS 26001-38-7)
- 7-Methyl-6-thioguanosine chloride (CAS 55727-10-1)
- 6-thioguanosine-5'-monophosphate (CAS 15867-02-4)
- Thioguanosine Diphosphate (CAS 16541-19-8)
- 6-Thioguanosine Triphosphate (CAS 17670-19-8)
- 6-Thioguanosine-5-O-monophosphate sodium salt (CAS 74686-78-5)
- 6-Thioguanosine hydrate (CAS 345909-25-3)
Recommended Standards
- 1,3-Dimethyl-5-((thiophen-2-ylmethyl)amino)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione (CAS 941914-81-4)
- 2-(Morpholin-4-yl)-6-(thiophen-3-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine (CAS 320415-99-4)
- 1,3-Dimethyl-5-((4-methylpiperazin-1-yl)sulfonyl)pyrimidine-2,4(1H,3H)-dione (CAS 874806-28-7)
- 2-(Pyridine-3-amido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid (CAS 314032-09-2)
- 1-(3-Chlorobenzyl)-1,2,3,4-tetrahydroquinoxalinedihydrochloride (CAS 939760-06-2)
- Thiophene-2,5-dicarboxylic acid monomethyl ester (CAS 38321-95-8)
- 3-((2-Fluorobenzyl)oxy)-5-nitro-1H-indazole (CAS 178160-29-7)
- 3-bromo-7-chloro-1H-pyrazolo[4,3-b]pyridine (CAS 1357946-80-5)
- 3-Bromo-alpha-chlorobenzaldoxime (CAS 86405-09-6)
- Ethyl (2Z)-2-azepan-2-ylidene-3-oxobutanoate (CAS 72611-25-7)
- 2-Bromo-4-methyl-N-(2,2,2-trifluoroethyl)aniline (CAS 1021071-01-1)
- 3-Amino-5-(4-methoxyphenyl)-1H,5H,6H-pyrazolo[4,3-c]pyridazin-6-one (CAS 338395-98-5)
- 4-(Difluoromethyl)-5-iodo-3-nitro-2-(trifluoromethoxy)pyridine (CAS 1804733-85-4)
- Semaglutide impurity 63 (CAS CATO-C4X-222663)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com