Azathioprine EP Impurity G (Thiamiprine) CAS 5581-52-2
| CAS No. | 5581-52-2 |
| Molecular Formula | C9H8N8O2S |
| Molecular Weight | 292.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Azathioprine EP Impurity G (Thiamiprine) (CAS 5581-52-2), a pharmacopoeial impurity reference standard (molecular formula C9H8N8O2S, MW 292.28 g/mol) used for the identification and quantification of trace impurities in APIs.
Azathioprine EP Impurity G (Thiamiprine) (C9H8N8O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Azathioprine EP Impurity G (Thiamiprine) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H8N8O2S |
| Molecular Weight | 292.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 8 |
| Sulfur Atoms | 1 |
Related Azathioprine Standards
- Azathioprine Impurity 18 (CAS 304441-06-3)
- Azathioprine Impurity 20 (CAS 302840-04-6)
- Azathioprine Impurity 17 (CAS CATO-C4X-146317)
- Azathioprine Impurity 14 (CAS 49808-20-0)
- Azathioprine-13C4 (CAS 1346600-71-2)
- Azathioprine-d3 (CAS 446-86-6 (Unlabeled))
- Azathioprine Impurity 25 (CAS CATO-C4X-146325)
- Azathioprine (CAS 446-86-6)
Recommended Standards
- 5-O-Benzoyl-1,2-di-O-isopropylidene-3-keto-alpha-D-xylofuranoside (CAS 6698-46-0)
- Ethyl 3-(benzyloxy)-2,4-difluorobenzoate (CAS 2635937-86-7)
- 5-Fluoro-2’-O-methyl-4-thiouridine (CAS 869355-51-1)
- Ethyl 5-(aminocarbonothioyl)-6-methyl-2-(trifluoromethyl)nicotinate (CAS 651292-55-6)
- Tretinoin Impurity 21 (CAS CATO-C4X-196921)
- Rifabutin EP Impurity D (CAS 62041-01-4)
- Dutasteride EP Impurity H (alfa-Dimer) (CAS CATO-C4X-110320)
- (S)-4-Methyloxazolidin-2-one 4042-35-7 MFCD06656589 SY037849 (CAS 4042-35-7)
- Indazole Impurity 3 (CAS 1801267-04-8)
- 2-(4-Chlorophenyl)-2-(pyrrolidin-1-yl)acetic acid (CAS 113346-67-1)
- Tirzepatide Impurity 51 (CAS CATO-C4X-324051)
- Methylnaltrexone Bromide Impurity 25 (CAS CATO-C4X-147525)
- 3-(1-Phenyl-3-(thiophen-2-yl)-1H-pyrazol-4-yl)acrylic acid (CAS 302581-52-8)
- Semaglutide Impurity 161 (x TFA Salt) (CAS CATO-C4X-2226161)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com