2-(4-Chlorophenyl)-2-(piperazin-1-yl)acetonitrile CAS 55829-50-0
| CAS No. | 55829-50-0 |
| Molecular Formula | C12H14ClN3 |
| Molecular Weight | 235.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(4-Chlorophenyl)-2-(piperazin-1-yl)acetonitrile is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(4-Chlorophenyl)-2-(piperazin-1-yl)acetonitrile (CAS 55829-50-0), molecular formula C12H14ClN3 and molecular weight 235.71 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(4-Chlorophenyl)-2-(piperazin-1-yl)acetonitrile (C12H14ClN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(4-Chlorophenyl)-2-(piperazin-1-yl)acetonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H14ClN3 |
| Molecular Weight | 235.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- 2-(3-chlorophenyl)-2-(piperazin-1-yl)acetonitrile (CAS 1017388-57-6)
- 1-[1-(4-chlorophenyl)-5-methyl-1h-pyrazol-4-yl]ethan-1-amine (CAS 1152950-12-3)
- [(4-chlorophenyl)methyl][(1-methyl-1h-pyrazol-4-yl)methyl]amine (CAS 1152953-78-0)
- 1-(5-(4-Chlorophenyl)-4-methyl-1h-imidazol-2-yl)ethan-1-amine (CAS 1156889-25-6)
- 1-(2-Chlorophenyl)-5-isopropyl-1h-pyrazol-4-amine (CAS 1245007-62-8)
- [(3-chlorophenyl)methyl][2-(1H-imidazol-1-yl)ethyl]amine (CAS 1249620-54-9)
- 1-(4-chlorophenyl)-5-(propan-2-yl)-1H-pyrazol-4-amine (CAS 1508227-54-0)
- (E)-1-(4-Chlorophenyl)-2-(1-methylpyrrolidin-2-ylidene)ethanone (CAS 75875-83-1)
Recommended Standards
- 1-[(2-chlorophenyl)methyl]-3,5-dimethyl-1h-pyrazol-4-amine (CAS 514801-03-7)
- 2-(4-Chlorophenyl)-4,4-dimethyl-3-oxopentanenitrile (CAS 88485-83-0)
- 1-(4-Chlorobutyl)quinolin-2(1H)-one (CAS 871300-06-0)
- 2-[[(6-Chloro-3-pyridinyl)methyl]amino]cyclopentanecarbonitrile (CAS 924669-64-7)
- tert-Butyl (2-(4-formylphenoxy)ethyl)carbamate (CAS 198990-09-9)
- (S)-2-((tert-Butoxycarbonyl)amino)-3-(4-(diethoxyphosphoryl)phenyl)propanoic acid (CAS 154483-81-5)
- 4-Bromo-2-(difluoromethyl)-6-(trifluoromethyl)nicotinaldehyde (CAS 1805261-51-1)
- 4-Methoxy-n-(propan-2-yl)aniline (CAS 16495-67-3)
- Difelikefalin Impurity 19 (CAS CATO-C4X-304119)
- 3-(4-(3,4-Dimethoxyphenyl)thiazol-2-yl)aniline (CAS 886495-70-1)
- 2-[2-[4-(Trifluoromethyl)phenyl]thiazol-4-yl]acetic Acid (CAS 17969-63-0)
- Methyl(2,2,3,3,3-pentafluoropropyl)amine (CAS 425-73-0)
- Tropisetron (CAS 89565-68-4)
- (His32,Leu34)-Neuropeptide Y (32-36) (CAS 168916-68-5)
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