6-Chloropyridine-3-thiol, 97% CAS 558466-12-9
| CAS No. | 558466-12-9 |
| Molecular Formula | C5H4ClNS |
| Molecular Weight | 145.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-Chloropyridine-3-thiol, 97% is closely related to a nitrile group, sulfur-containing functionality, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-Chloropyridine-3-thiol, 97% (CAS 558466-12-9) is a high-purity analytical reference standard with the molecular formula C5H4ClNS and a molecular weight of 145.61 g/mol.
The molecular framework of 6-Chloropyridine-3-thiol, 97% (C5H4ClNS) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Chloropyridine-3-thiol, 97% meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H4ClNS |
| Molecular Weight | 145.61 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloropyridine Standards
- 2-Chloropyridine-4-thiol (CAS 106962-88-3)
- 3-Chloropyridine-4-thiol (CAS 1247828-52-9)
- 2-Chloropyridine-3-thiol (CAS 74198-95-1)
- 3-Chloropyridine-2-thiol (CAS 5897-94-9)
- 4-Chloropyridine-2-thiol (CAS 204996-08-7)
- 3-Chloropyridine-2,4-diol (CAS 103792-81-0)
- 6-Chloropyridine-3,4-diol (CAS 1196156-68-9)
- 2-Chloropyridine-3,5-diol (CAS 1227573-04-7)
Recommended Standards
- 3-Chloro-6,6-dimethyl-3-azabicyclo[3.1.0]Hexane (CAS 1159791-82-8)
- 5-Chloro-2,2-dimethylpentanenitrile (CAS 4207-54-9)
- 5-chloro-2-ethenylpyridine (CAS 223445-06-5)
- 7-Chloroheptanenitrile (CAS 22819-91-6)
- 2-Amino-1-propylbenzimidazole (CAS 57667-50-2)
- (1-(Aminomethyl)-2-(4-fluorophenyl)cyclopropyl)methanol (CAS 1269528-80-4)
- 4-(2-Chlorophenyl)piperidine-4-carbonitrile (CAS 191328-21-9)
- Polymyxin B2 XTFA Salt (CAS 34503-87-2 (free base))
- 2,6-Di-tert-butylmorpholine oxalate (CAS 2034157-35-0)
- 3-(Methylsulfanyl)propane-1-thiol (CAS 26718-09-2)
- 1-(5-Fluoro-2-(2-methyl-1h-imidazol-1-yl)phenyl)ethan-1-one (CAS 1019622-64-0)
- 5-Amino-6-methylpyrazine-2-carbonitrile (CAS 1374652-05-7)
- 2-Amino-3-(5-methyl-2-thienyl)propionic Acid (CAS 74348-36-0)
- Semaglutide Impurity 191 (CAS CATO-C4X-2226191)
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