(2-Aminothiophen-3-yl)(4-chlorophenyl)methanone CAS 55865-51-5
| CAS No. | 55865-51-5 |
| Molecular Formula | C11H8ClNOS |
| Molecular Weight | 237.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(2-Aminothiophen-3-yl)(4-chlorophenyl)methanone (CAS 55865-51-5), molecular formula C11H8ClNOS and molecular weight 237.71 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2-Aminothiophen-3-yl)(4-chlorophenyl)methanone (C11H8ClNOS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H8ClNOS |
| Molecular Weight | 237.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Aminothiophen Standards
- (2-Aminothiophen-3-yl)(3-chlorophenyl)methanone (CAS 399043-49-3)
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- (2-Aminothiophen-3-yl)(4-methoxyphenyl)methanone (CAS 436093-36-6)
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Recommended Standards
- (2-Chloropyridin-3-yl)(3-methylthiophen-2-yl)methanone (CAS 760192-99-2)
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- N-(4-Chlorophenyl)thiophene-2-carboxamide (CAS 15950-35-3)
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- 2,2,2-Trifluoroethyl (5-chloropyridin-2-yl)carbamate (CAS 1087788-67-7)
- 2-[3-(2,4-Dichloro-phenyl)-propyl]-6-methoxy-benzoic acid methyl ester (CAS 1171923-45-7)
- Ethyl 4-methoxy-1H-indole-2-carboxylate (CAS 43142-25-2)
- 1-Methyl-2,6-dioxo-N-(4-(trifluoromethyl)phenyl)-1,2,3,6-tetrahydropyrimidine-4-carboxamide (CAS 338774-76-8)
- 2-((2,3-Dihydro-1H-inden-5-yl)amino)-2-oxoethyl 2-(methylthio)nicotinate (CAS 562800-17-3)
- tert-Butyl 3-[(benzylamino)methyl]-4-hydroxypyrrolidine-1-carboxylate (CAS 1858255-37-4)
- 2-(7-Carboxy-4-methylheptoxy)carbonylcyclohexane-1-carboxylic acid (CAS 1637562-51-6)
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