4-Chloro-6-methoxy-2-(methylthio)-5-nitropyrimidine CAS 56032-35-0
| CAS No. | 56032-35-0 |
| Molecular Formula | C6H6ClN3O3S |
| Molecular Weight | 235.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Chloro-6-methoxy-2-(methylthio)-5-nitropyrimidine (C6H6ClN3O3S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 4-Chloro-6-methoxy-2-(methylthio)-5-nitropyrimidine (CAS 56032-35-0), a certified reference material (molecular formula C6H6ClN3O3S, MW 235.65 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloro-6-methoxy-2-(methylthio)-5-nitropyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6ClN3O3S |
| Molecular Weight | 235.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 6-Chloro-2-(methylsulfonyl)pyrimidine-4-carboxamide (CAS 7251-25-4)
- N-[(2-Chloro-5-thiazolyl)methyl]-N＇-nitroguanidine (CAS 135018-15-4)
- 3-Chloro-4-(difluoromethoxy)-N-isopropylaniline (CAS 1042521-11-8)
- (2-chloro-5-methyl-4-nitro-phenyl) acetate (CAS 2231674-06-7)
- 2-Chloro-5-(2-fluorobenzoyl)pyridine (CAS 1187167-94-7)
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- (3-Chloro-5-fluorophenyl)(pyridin-2-yl)methanone (CAS 1261754-42-0)
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Recommended Standards
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- n-(1h-Pyrazol-4-yl)acetamide (CAS 6647-92-3)
- 1-Morpholinobutane-1,3-dione (CAS 16695-54-8)
- 4-(Aminomethyl)-1-benzylpyrrolidin-2-one hemifumarate (CAS 97205-35-1)
- 4-Oxo-1,4-dihydrothieno[2,3-d]pyrimidine-5-carboxamide (CAS 1801143-25-8)
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- Semaglutide (CAS CATO-C4X-2226105)
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