4,6-Dichloropyrimidine-2,5-diamine hydrochloride CAS 56145-03-0
| CAS No. | 56145-03-0 |
| Molecular Formula | C4H4Cl2N4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4,6-Dichloropyrimidine-2,5-diamine hydrochloride (CAS 56145-03-0), a certified reference material (molecular formula C4H4Cl2N4HCl, MW 215.46 g/mol) for analytical method development and quality control.
Owing to a nitrile group, chlorine substitution, 4,6-Dichloropyrimidine-2,5-diamine hydrochloride is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 215.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H4Cl2N4 HCl |
| Molecular Weight | 215.46 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Dichloropyrimidine Standards
- Ethyl 5,6-dichloropyrimidine-4-carboxylate (CAS 1097250-57-1)
- 4-Butyl-2,6-dichloropyrimidine (CAS 115419-76-6)
- 4,6-Dichloropyrimidine (CAS 1193-21-1)
- Sodium 4,6-dichloropyrimidine-5-carboxylate (CAS 1204295-88-4)
- methyl 2,5-dichloropyrimidine-4-carboxylate (CAS 1206249-62-8)
- 4,6-Dichloropyrimidine-5-sulfonyl chloride (CAS 1216003-03-0)
- 2,4-dichloropyrimidine-5-carboxamide (CAS 1240390-28-6)
- 2,5-Dichloropyrimidine-4-carboxylic acid (CAS 1240594-41-5)
Recommended Standards
- 3-Bromo-4-nitroaniline (CAS 40787-96-0)
- 7-Aminoquinolin-8-ol (CAS 18472-06-5)
- 5-Bromoisothiazol-3-amine (CAS 2387239-22-5)
- 2-(2,5-Dichloropyridin-4-yl)pyrimidine-5-carboxylic acid (CAS 1416439-33-2)
- H-β-Fluoro-DL-Ala-OH (CAS 16652-37-2)
- 6-(Prop-2-yn-1-yloxy)pyridin-3-amine (CAS 1198007-00-9)
- Chlorocyclodecane (CAS 7541-62-0)
- 1-(2-hydroxyethyl)-1H-1,2,3-triazole-4-carboxamide (CAS 1795430-31-7)
- (R)-3-(2,2,5,5-Tetramethyl-1,3-dioxane-4-carboxamido)propanoic acid (CAS 167308-62-5)
- Peptide Impurity 26 (CAS 1350456-66-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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