N-Nitroso-3-hydroxy pyrrolidone CAS 56222-35-6
| CAS No. | 56222-35-6 |
| Molecular Formula | C4H8N2O2 |
| Molecular Weight | 116.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-Nitroso-3-hydroxy pyrrolidone.
CATO supplies N-Nitroso-3-hydroxy pyrrolidone (CAS 56222-35-6), a certified reference material (molecular formula C4H8N2O2, MW 116.12 g/mol) for analytical method development and quality control.
N-Nitroso-3-hydroxy pyrrolidone (C4H8N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-Nitroso-3-hydroxy pyrrolidone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H8N2O2 |
| Molecular Weight | 116.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1973 |
| Nitrogen Atoms | 2 |
Related N Standards
- N-Nitroso-methyl-isobutyl-amine (CAS 34419-76-6)
- N-Nitroso-methyl-tertbutyl-amine (CAS 2504-18-9)
- N-Nitroso N-Ethyl N-Propyl Amine (CAS 25413-61-0)
- N-Nitroso methyl butyl amine (CAS 7068-83-9)
- N-Nitroso-N-ethyl Urea, Contains 40% water, 1.8 % AcOH (CAS 759-73-9)
- N-Nitroso Tosufloxacin impurity 7 (CAS CATO-C4X-19767)
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Recommended Standards
- N-Acetylglycinamide (CAS 2620-63-5)
- Olmesartan Impurity 10 (CAS 4437-70-1)
- N,N'-Dimethyloxamide (CAS 615-35-0)
- oxetan-3-yl acetate (CAS 39267-83-9)
- 4-Methanesulfonyl-3-(morpholin-4-yl)aniline (CAS 942474-45-5)
- tert-Butyl 3-((2-bromobenzyl)amino)pyrrolidine-1-carboxylate (CAS 887578-18-9)
- 1-(4-chloro-3-fluorophenyl)-1H,4H,5H,6H-cyclopenta[c]pyrazole-3-carboxylic acid (CAS 1275532-60-9)
- N-((5-bromopyridin-3-yl)methyl)-2-methoxyethan-1-amine (CAS 1246034-49-0)
- 2,4-Diisocyanato-1,3,5-trimethylbenzene (CAS 16959-10-7)
- tert-Butyl 6-bromospiro[1,2-dihydroindene-3,4'-piperidine]-1'-carboxylate (CAS 1160247-40-4)
- (S)-1-(((9H-fluoren-9-yl)methoxy)carbonyl)-3-benzylpiperidine-3-carboxylic acid (CAS 1354752-82-1)
- Methyl 4-bromo-1H-pyrrolo[2,3-c]pyridine-7-carboxylate (CAS 2460708-45-4)
- 4-((7-Fluoro-9-oxo-9H-fluoren-2-yl)amino)-4-oxobut-2-enoic acid (CAS 7255-73-4)
- Acetyl Hexapeptide-39 (CAS 1382088-38-1)
Why CATO?
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