1-(4-Chloro-3-nitrobenzoyl)piperazine CAS 563538-35-2
| CAS No. | 563538-35-2 |
| Molecular Formula | C11H12ClN3O3 |
| Molecular Weight | 269.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 269.68 g/mol gives 1-(4-Chloro-3-nitrobenzoyl)piperazine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(4-Chloro-3-nitrobenzoyl)piperazine (CAS 563538-35-2), molecular formula C11H12ClN3O3 and molecular weight 269.68 g/mol, is a CATO reference standard with documented purity and traceability.
1-(4-Chloro-3-nitrobenzoyl)piperazine (C11H12ClN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12ClN3O3 |
| Molecular Weight | 269.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
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- Ethyl 4-chloro-5-hydroxy-2,7-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate (CAS 1269117-94-3)
- 4-Chloro-1-methoxy-2-nitro-8,9-dihydro-5H-benzo[7]annulen-7(6H)-one (CAS 1354545-56-4)
- 7-Chloro-4,6-dimethoxy-1-methyl-1H-indole-2-carboxylic acid (CAS 1361003-79-3)
- Methyl 7-chloro-4,6-dimethoxy-1H-indole-2-carboxylate (CAS 1361004-17-2)
- Ethyl 2-(7-chloro-3-oxo-2H-benzo[b][1,4]oxazin-4(3H)-yl)acetate (CAS 139605-37-1)
- 3-(7-Chloro-2-methyl-3-oxo-2H-benzo[b][1,4]oxazin-4(3H)-yl)propanoic acid (CAS 1499913-65-3)
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Recommended Standards
- 1-(3-Chloro-4-methoxyphenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 63674-98-6)
- 1-(5-Chloro-methoxyphenyl)-5-oxo-3-pyrrolidinecarboxylic acid (CAS 63675-21-8)
- 2-((2-Chloro-4-nitrophenyl)amino)-N-cyclopropylacetamide (CAS 923224-03-7)
- (3R,4S)-4-(2-chloro-4-methoxyphenyl)-2-oxopyrrolidine-3-carboxylic acid (CAS 1784747-76-7)
- Ethyl 3-amino-4-methyl-5-nitrobenzoate (CAS 99069-09-7)
- Tetraethylphosphoniumtrifluoromethanesulfonate (CAS 111928-06-4)
- (E)-3-methyl-1-(3-oxo-3-phenylprop-1-en-1-yl)pyridin-1-ium chloride (CAS 19518-26-4)
- Methyl 2-(5-bromo-3,3-dimethyl-2-oxoindolin-1-yl)acetate (CAS 1263213-65-5)
- 1-(2-Methylbenzyl)-1H-pyrazol-4-ol (CAS 1603517-86-7)
- Methyl 2-((tert-butoxycarbonyl)amino)-3-hydroxybutanoate (CAS 1838578-68-9)
- 4-((Phenylimino)methyl)-5-(trifluoromethyl)-1,2-dihydro-3H-pyrazol-3-one (CAS 339020-96-1)
- Hemokinin 1 (human) (CAS 491851-53-7)
- Fmoc-3-amino-L-tyrosine (CAS 726181-70-0)
- Semaglutide Impurity 157 (x TFA Salt) (CAS CATO-C4X-2226157)
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