2-bromo-1-methyl-1H-pyrrole CAS 56454-27-4
| CAS No. | 56454-27-4 |
| Molecular Formula | C5H6BrN |
| Molecular Weight | 160.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-bromo-1-methyl-1H-pyrrole is closely related to a nitrile group, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-bromo-1-methyl-1H-pyrrole (CAS 56454-27-4) is a high-purity analytical reference standard with the molecular formula C5H6BrN and a molecular weight of 160.01 g/mol.
The molecular framework of 2-bromo-1-methyl-1H-pyrrole (C5H6BrN) is characterized by a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-bromo-1-methyl-1H-pyrrole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H6BrN |
| Molecular Weight | 160.01 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related bromo Standards
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- 3-Bromo-1-methyl-1H-pyrrole (CAS 77123-94-5)
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Recommended Standards
- 1-bromocyclobutanecarbonitrile (CAS 39994-98-4)
- 3-(Bromomethyl)-1H-pyrrole (CAS 807621-31-4)
- 1-(Bromomethyl)cyclopropanecarbonitrile (CAS 98730-78-0)
- 3-bromocyclobutanecarbonitrile (CAS 1824469-41-1)
- Methyl 5-bromo-2,3-dihydro-1H-pyrrolizine-7-carboxylate (CAS 1783330-05-1)
- 3-(Difluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazole (CAS 1626337-82-3)
- (11β,13α)-17-(Acetyloxy)-11-[4-(dimethylamino)phenyl]-19-norpregna-4,9-diene-3,20-dione (CAS 96285-40-4)
- 7-(Chloromethyl)benzo[d]isothiazole (CAS 2021538-99-6)
- Dimethylarsinothioic Acid (CAS 754217-65-7)
- 4,7-Dibromo-5-methylbenzo[c][1,2,5]thiadiazole (CAS 2255-79-0)
- 4-Methyl-2,3-dihydrothiophene 1,1-Dioxide (CAS 872-94-6)
- 4-(5-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyrazin-2-yl)-6-(6-oxo-3,6-dihydro-2H-pyran-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile (CAS CATO-C3D-262971)
- 4-MethylumbelliFeryl pyrophosphate diester diSodium salt (CAS 84282-11-1)
- (Des-Thr?)-Glucagon trifluoroacetate salt (CAS 1802078-27-8)
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