3-[Benzyl-(2-methoxy-phenyl)-sulfamoyl]-4-chloro-benzoic acid CAS 565166-97-4
| CAS No. | 565166-97-4 |
| Molecular Formula | C21H18ClNO5S |
| Molecular Weight | 431.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-[Benzyl-(2-methoxy-phenyl)-sulfamoyl]-4-chloro-benzoic acid (C21H18ClNO5S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 3-[Benzyl-(2-methoxy-phenyl)-sulfamoyl]-4-chloro-benzoic acid (CAS 565166-97-4), a certified reference material (molecular formula C21H18ClNO5S, MW 431.89 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-[Benzyl-(2-methoxy-phenyl)-sulfamoyl]-4-chloro-benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H18ClNO5S |
| Molecular Weight | 431.89 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Benzyl Standards
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Recommended Standards
- (E)-3-(2-chlorophenyl)-N-(4-(N-(3,4-dimethylisoxazol-5-yl)sulfamoyl)phenyl)acrylamide (CAS 873307-19-8)
- 3-[benzyl(4-methoxyphenyl)sulfamoyl]-4-chlorobenzoic acid (CAS 565173-05-9)
- ((4-(2-Chlorophenoxy)phenyl)sulfonyl)phenylalanine (CAS 1009715-73-4)
- 5-[benzyl(4-methoxyphenyl)sulfamoyl]-2-chlorobenzoic acid (CAS 565198-70-1)
- 2-Chloro-N-(2,5-dimethoxyphenyl)-N-methylquinazolin-4-amine (CAS 827030-71-7)
- 1-methyl-3-(trifluoromethyl)-1H-pyrazolo[4,3-c]pyridine (CAS 230305-87-0)
- 3,4-Dichloro-N-(2-fluorobenzyl)aniline (CAS 723753-73-9)
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