1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile CAS 568553-93-5
| CAS No. | 568553-93-5 |
| Molecular Formula | C16H11FN2O3 |
| Molecular Weight | 298.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile (CAS 568553-93-5), molecular formula C16H11FN2O3 and molecular weight 298.27 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile (C16H11FN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H11FN2O3 |
| Molecular Weight | 298.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Cyclopropyl Standards
- 3-Cyclopropyl-6-(2-fluorophenyl)-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 954277-06-6)
- 3-Cyclopropyl-6-(4-fluorophenyl)-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 953730-51-3)
- 1-Cyclopropyl-2,2,2-trifluoroethyl 2H-chromene-3-carboxylate (CAS 1384630-04-9)
- 1-(4-Cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl)-1H-pyrazole-3-carboxylic acid (CAS 1006448-08-3)
- 1-Cyclopropyl-5-amino-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid (CAS 103772-14-1)
- 1-(2-Cyclopropyl-6-(trifluoromethyl)pyrimidin-4-yl)-1H-imidazole-4-carboxylic acid (CAS 1707373-02-1)
- 1-(2-Cyclopropyl-6-(trifluoromethyl)pyrimidin-4-yl)-1H-pyrazole-3-carboxylic acid (CAS 1707566-49-1)
- N-Cyclopropyl-2-(3-cyclopropyl-5-oxo-4-phenyl-4,5-dihydro-1H-1,2,4-triazol-1-yl)acetamide (CAS 1396808-26-6)
Recommended Standards
- 1-(4-{[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]oxy}phenyl)ethan-1-one (CAS 866150-25-6)
- 1H-Indol-3-yl (2-(trimethylammonio)ethyl) phosphate (CAS 439809-44-6)
- 1-(2-Methyl-4-sulfophenyl)-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylic acid (CAS 67939-25-7)
- 2-(4-fluorophenoxy)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde (CAS 879906-49-7)
- N2,N4,N6-Tri(pyridin-2-yl)-1,3,5-triazine-2,4,6-triamine (CAS 67297-95-4)
- 5-[(2-chlorobenzyl)oxy]-2-hydroxybenzoic acid (CAS 16094-45-4)
- ((4-Methoxyphenyl)sulfonyl)methionine (CAS 1396967-23-9)
- Thiazolylmethyl-4-nitrophenylcarbonate-13C3 (CAS 1189969-30-9)
- 3-Phenyl-5-[(2,4,5-trichlorophenoxy)methyl]-1,2-oxazole (CAS 478066-43-2)
- Brivaracetam Impurity 183 (CAS CATO-C4X-2007183)
- 1,5-Dimethoxypentane (CAS 111-89-7)
- (S)-1-(2,3-dimethylphenyl)-2-methylpropan-1-amine (CAS 1213330-88-1)
- (S)-4-Amino-2-(benzylamino)-4-oxobutanoic acid (CAS 46741-77-9)
- Palmitoyl Tetrapeptide-7 (CAS 221227-05-0)
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