2-Methylimidazo[1,2-a]pyrazin-3-amine hydrochloride CAS 56888-71-2
| CAS No. | 56888-71-2 |
| Molecular Formula | C7H8N4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Methylimidazo[1,2-a]pyrazin-3-amine hydrochloride (CAS 56888-71-2), molecular formula C7H8N4HCl and molecular weight 184.63 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Methylimidazo[1,2-a]pyrazin-3-amine hydrochloride (C7H8N4HCl) is characterized by a nitrile group, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H8N4 HCl |
| Molecular Weight | 184.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Methylimidazo Standards
- 2-Methylimidazo[1,2-a]pyridin-6-ol (CAS 1001434-68-9)
- 2-Methylimidazo[1,2-a]pyridin-7-ol (CAS 1001434-77-0)
- 3-Methylimidazo[1,2-a]pyridine-2-carbaldehyde (CAS 1001754-85-3)
- 1-(2-Methylimidazo[1,2-a]pyrimidin-3-yl)ethanone (CAS 100289-21-2)
- 5-Methylimidazo[1,2-a]pyridin-2-amine (CAS 1005785-43-2)
- 5-methylimidazo[2,1-b]thiazole-6-carboxylic acid (CAS 1007874-71-6)
- 3-methylimidazo[2,1-b]thiazole-5-carboxylic acid (CAS 1007874-80-7)
- 2-methylimidazo[2,1-b]thiazole-5-carboxylic acid (CAS 1007874-97-6)
Recommended Standards
- (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(naphthalen-2-yl)butanoic acid (CAS 269398-91-6)
- tert-Butyl 4-amino-4-(aminomethyl)piperidine-1-carboxylate (CAS 871115-32-1)
- Ethyl 4-methyl-1H-pyrazole-5-carboxylate (CAS 856061-38-6)
- 1-(3-Bromopropyl)-4,4-difluoropiperidine hydrobromide (CAS 2138232-64-9)
- 3,5-Dimethyl-1-(2-(trifluoromethoxy)ethyl)-1h-pyrazol-4-amine (CAS 1489065-03-3)
- 3-(Hept-1-en-1-yl)-2-methylquinolin-4(1H)-one (CAS 36970-31-7)
- 2-(Difluoromethyl)-4-hydroxy-3-(trifluoromethyl)pyridine-6-methanol (CAS 1804867-57-9)
- 7-Chloro-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[3,2-b]pyridine (CAS 1260385-95-2)
- tert-butyl 2-(N-hydroxycarbamimidoyl)azepane-1-carboxylate (CAS 1461726-87-3)
- (Ser(PO?H?)2?2)-Tau Peptide (260-264) PAb Blocking trifluoroacetate salt (CAS 2022956-57-4)
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