Methyl 3-Chloro-4-hydroxyphenylacetate CAS 57017-95-5
| CAS No. | 57017-95-5 |
| Molecular Formula | C9H9ClO3 |
| Molecular Weight | 200.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 3-Chloro-4-hydroxyphenylacetate (CAS 57017-95-5) is a high-purity analytical reference standard with the molecular formula C9H9ClO3 and a molecular weight of 200.62 g/mol.
The molecular framework of Methyl 3-Chloro-4-hydroxyphenylacetate (C9H9ClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H9ClO3 |
| Molecular Weight | 200.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl-containing |
Related Methyl Standards
- 2-(4-Chloro-3-cyclopropyl-1H-pyrazol-1-yl)acetic acid (CAS 1006319-36-3)
- 5-Chloro-6-(ethylamino)pyridine-3-carboxylic acid (CAS 1019461-54-1)
- 2-Chloro-6-ethoxybenzoic acid (CAS 1020998-62-2)
- Methyl 2-Chloro-5-(Methylamino)Isonicotinate (CAS 1034131-90-2)
- Methyl 2-chloro-4-methoxybenzoate (CAS 104253-45-4)
- 1-(3-Chloro-2-hydroxy-5-(hydroxymethyl)phenyl)ethanone (CAS 109201-11-8)
- 6- Chloro- 2- ethylaminonicotinic Acid (CAS 1092523-21-1)
- 5-chloro-4-methoxy-2-methylbenzoic acid (CAS 109803-47-6)
Recommended Standards
- Methyl 3-chloro-4-hydroxy-5-methylbenzoate (CAS 883241-62-1)
- Methyl 3-chloro-4-methoxybenzoate (CAS 37908-98-8)
- methyl 3-chloro-4-hydrazinylbenzoate (CAS 883194-89-6)
- Methyl 3-chloro-5-methoxybenzoate (CAS 96826-41-4)
- 5-Cyclopropoxy-4-ethylpyridin-2-amine (CAS 1243375-35-0)
- N-(7-acetyl-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide (CAS 63546-20-3)
- 3-(Cyclobutylmethoxy)isonicotinic acid (CAS 1539966-56-7)
- benzyl 4-(benzyloxycarbonylamino)-2,7-diazaspiro[4.4]nonane-2-carboxylate (CAS 2306275-96-5)
- Tert-butyl 4-(3,5-dimethoxyphenyl)piperazine-1-carboxylate (CAS 1121596-71-1)
- Ethyl 1-(4-bromobenzyl)-5-methyl-1H-1,2,3-triazole-4-carboxylate (CAS 852180-99-5)
- 5-Bromo-N-isopropylthiophene-2-carboxamide (CAS 908494-87-1)
- 5-(Methothio)thiophene-2-boronic acid pinacol ester (CAS 1172999-13-1)
- 1-Cyclohexyl-1h-pyrazol-4-amine (CAS 97421-23-3)
- (Des-Bromo)-Neuropeptide B (1-23) (human) (CAS 434897-64-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com