2-Chloro-N-(3-((3-chlorobiphenyl-4-yl)methyl)-2-ethyl-4-oxo-3,4-dihydroquinazolin-6-yl)benzamide CAS 570373-45-4
| CAS No. | 570373-45-4 |
| Molecular Formula | C31H25Cl2N3O2 |
| Molecular Weight | 542.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-N-(3-((3-chlorobiphenyl-4-yl)methyl)-2-ethyl-4-oxo-3,4-dihydroquinazolin-6-yl)benzamide (CAS 570373-45-4), molecular formula C31H25Cl2N3O2 and molecular weight 542.46 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 2-Chloro-N-(3-((3-chlorobiphenyl-4-yl)methyl)-2-ethyl-4-oxo-3,4-dihydroquinazolin-6-yl)benzamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 542.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-N-(3-((3-chlorobiphenyl-4-yl)methyl)-2-ethyl-4-oxo-3,4-dihydroquinazolin-6-yl)benzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C31H25Cl2N3O2 |
| Molecular Weight | 542.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 2-Chloro-N-[3-[(3’-chloro[1,1’-biphenyl]-4-yl)methyl]-3,4-dihydro-4-oxo-2-propyl-6-quinazolinyl]-benzamide (CAS 1797131-01-1)
- 4-Chloro-N-(2-((4-chlorobenzylidene)amino)-1,2-bis(4-chlorophenyl)ethyl)benzamide (CAS 115294-32-1)
- (E)-3-(2-Chloro-4-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid (CAS 1089660-72-9)
- N-(3-Chloro-4-methoxyphenyl)-2-((3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 477329-66-1)
- 2-((5-(6-Chloro-3-pyridyl)-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazole-3-yl)thio-1-[3-(trifluoromethyl)phenyl]ethan-1-one (CAS 680217-03-2)
- (4Z)-4-({[2-chloro-5-(trifluoromethyl)phenyl]amino}methylidene)-2-[(2,4-dichlorophenyl)methoxy]-1,2,3,4-tetrahydroisoquinoline-1,3-dione (CAS 338396-47-7)
- 1-(3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-3-(2,4-dichlorobenzyl)-4-hydroxypyridin-2(1H)-one (CAS 866049-47-0)
- 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}phenyl 3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carboxylate (CAS 339020-00-7)
Recommended Standards
- 2-Bromo-N-(4-(methylthio)-1-(2-(2-morpholinothiazole-4-carbonyl)hydrazinyl)-1-oxobutan-2-yl)benzamide (CAS 1139885-23-6)
- (S)-(6,6'-Dimethoxybiphenyl-2,2'-diyl)bis(di-2-furylphosphine) (CAS 145214-59-1)
- 4,4',4"-Boranetriyltris(2,3,5,6-tetramethylbenzoic acid) (CAS 1358822-48-6)
- (R)-(6,6'-Dimethoxybiphenyl-2,2'-diyl)bis(di-2-furylphosphine) (CAS 145214-57-9)
- 2-[(Pyridin-3-ylmethyl)amino]propanoic acid (CAS 1396966-76-9)
- N,N-DImethyl-6-piperidin-4-ylpyridine-2-carboxamide dihydrochloride (CAS 1858242-40-6)
- Minocycline EP Impurity A (HCl salt) (CAS 179471-96-6)
- Dolutegravir Impurity 54 (CAS CATO-C4X-162054)
- tert-Butyl 4-((aminooxy)methyl)piperidine-1-carboxylate (CAS 143540-02-7)
- 4-Amino-6-methoxynicotinonitrile (CAS 686278-89-7)
- 4-Fluoro-3'-methyl-[1,1'-biphenyl]-3-carbaldehyde (CAS 1183311-26-3)
- 1-(5-Amino-4-fluoro-2-hydroxyphenyl)ethanone (CAS 2090484-64-1)
- (3,4-Difluorophenyl)(2-(morpholinomethyl)phenyl)methanone (CAS 898751-17-2)
- Semaglutide impurity 60 (CAS CATO-C4X-222660)
Why CATO?
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