7-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide CAS 57071-77-9
| CAS No. | 57071-77-9 |
| Molecular Formula | C12H14N4O5 |
| Molecular Weight | 294.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide.
CATO supplies 7-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide (CAS 57071-77-9), a certified reference material (molecular formula C12H14N4O5, MW 294.26 g/mol) for analytical method development and quality control.
The molecular framework of 7-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide (C12H14N4O5) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14N4O5 |
| Molecular Weight | 294.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Nitrogen Atoms | 4 |
Recommended Standards
- 6-Nitro-2-phenylquinoline-4-carboxylic Acid (CAS 871883-56-6)
- 7-(3-Carboxypyridin-2-yl)quinolizin-5-ium-1-carboxylate (CAS 399017-38-0)
- 5-Nitro-2-(4-vinylphenyl)isoindoline-1,3-dione (CAS 89014-97-1)
- 8-Nitro-2-phenylquinoline-4-carboxylic Acid (CAS 92566-37-5)
- (4-Fluorophenyl)(3-methylpiperidin-1-yl)methanone (CAS 330469-25-5)
- Methyl 1-(2-cyanoethyl)-6-(4-methoxyphenyl)-3-methyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1018051-61-0)
- 4-Amino-2-(cyclohexyloxy)benzamide (CAS 1369903-06-9)
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- Methyl 3-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-carboxylate (CAS 1031667-63-6)
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- CGMP Dependent Kinase Inhibitor Peptide (CAS 82801-73-8)
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