4-Bromonaphthalen-1-ol CAS 571-57-3
| CAS No. | 571-57-3 |
| Molecular Formula | C10H7BrO |
| Molecular Weight | 223.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Bromonaphthalen-1-ol is closely related to a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-Bromonaphthalen-1-ol (CAS 571-57-3), a certified reference material (molecular formula C10H7BrO, MW 223.07 g/mol) for analytical method development and quality control.
The molecular framework of 4-Bromonaphthalen-1-ol (C10H7BrO) is characterized by a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H7BrO |
| Molecular Weight | 223.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Br-containing |
Related Bromonaphthalen Standards
- 3-bromonaphthalen-1-ol (CAS 90767-17-2)
- 8-Bromonaphthalen-2-ol (CAS 7385-87-7)
- 7-Bromonaphthalen-2-ol (CAS 116230-30-9)
- 5-Bromonaphthalen-2-amine (CAS 116400-84-1)
- 7-Bromonaphthalen-1-amine (CAS 136924-78-2)
- 8-bromonaphthalen-2-amine (CAS 167275-44-7)
- 1-Bromonaphthalen-2-amine (CAS 20191-75-7)
- 3-Bromonaphthalen-2-amine (CAS 54245-33-9)
Recommended Standards
- ethyl 5-bromo-1H-imidazole-4-carboxylate (CAS 944906-76-7)
- 875-51-4 Aniline, 4-bromo-2-nitro- Benzenamine, 4-bromo-2-nitro- 3-12-00-01670 (Beilstein Handbook Reference) AI3-15013 BRN 2210198 p-Bromo-o-nitroaniline 4-Bromo-o-nitroaniline 4-Bromo-2-nitroaniline 4-Bromo-2-nitrobenzeneamine 2-Nitro-4-bromoaniline NSC 10069 NSC 37396 (CAS 875-51-4)
- Bromo-2-Naphthalenol (CAS 63980-30-3)
- 6-Bromo-1-hydroxynaphthalene (CAS 91270-68-7)
- 3-Ethylquinazoline-2,4(1H,3H)-dione (CAS 2217-26-7)
- (R)-Dibenzyl 2-aminopentanedioate hydrochloride (CAS 146844-02-2)
- 2-Chloro-6-methyl-N-(piperidin-4-yl)pyrimidin-4-amine (CAS 1000335-21-6)
- 2,3-Dihydro-N-2-propen-1-yl-1,4-benzodioxin-6-sulfonamide (CAS 333446-76-7)
- 2-((Furan-2-ylmethyl)amino)-4-phenylpyrimidine-5-carboxylic acid (CAS 862838-46-8)
- Methyl 3-(hydroxymethyl)picolinate (CAS 1279821-42-9)
- 4-Cyclopropoxyisophthalaldehyde (CAS 1243328-93-9)
- Ethyl 4-(3-(trifluoromethyl)pyridin-2-yl)piperazine-1-carboxylate (CAS 260367-79-1)
- 2-[1-(aminomethyl)cyclopentyl]acetic acid hydrochloride (CAS 63562-09-4)
- Semaglutide impurity 69 (CAS CATO-C4X-222669)
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