6-Amino-3-ethyl-1,2,3,4-tetrahydro-β,2,4-trioxo-1-(phenylmethyl)-5-pyrimidinepropanenitrile CAS 571149-75-2
| CAS No. | 571149-75-2 |
| Molecular Formula | C16H16N4O3 |
| Molecular Weight | 312.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Amino-3-ethyl-1,2,3,4-tetrahydro-β,2,4-trioxo-1-(phenylmethyl)-5-pyrimidinepropanenitrile (CAS 571149-75-2), molecular formula C16H16N4O3 and molecular weight 312.32 g/mol, is a CATO reference standard with documented purity and traceability.
6-Amino-3-ethyl-1,2,3,4-tetrahydro-β,2,4-trioxo-1-(phenylmethyl)-5-pyrimidinepropanenitrile (C16H16N4O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H16N4O3 |
| Molecular Weight | 312.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Nitrogen Atoms | 4 |
Related Amino Standards
- 2-Amino-3-(benzophenone-4-carboxamido)-propanoic Acid (CAS 1219200-12-0)
- Methyl 2-amino-7-isopropyl-5-oxochromeno[2,3-b]pyridine-3-carboxylate (CAS 1820640-27-4)
- 1-Amino-4,8-dihydroxy-5-(isopropylamino)anthracene-9,10-dione (CAS 69093-18-1)
- 1-Amino-5,8-dihydroxy-4-(isopropylamino)anthracene-9,10-dione (CAS 58608-11-0)
- 4-(2-Amino-7-oxo-4-phenyl-5H-pyrrolo[3,4-d]pyrimidin-6(7H)-yl)butanoic acid (CAS 76628-78-9)
- 6-Amino-1-benzyl-5-[(furan-2-ylmethyl)amino]-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 726165-23-7)
- 6-Amino-4-(2,4-dimethoxyphenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile (CAS 89607-46-5)
- 7-Amino-1-benzyl-3-ethyl-1H,2H,3H,4H,5H,8H-pyrido[2,3-d]pyrimidine-2,4,5-trione (CAS 571149-80-9)
Recommended Standards
- 6,7-Dimethoxy-1-(2-nitrophenyl)-3,4-dihydroisoquinoline (CAS 60888-85-9)
- 6-Methyl-4-oxo-9-(2-phenylhydrazono)-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acid (CAS 70999-42-7)
- 6,2',4'-Trimethoxyflavone (CAS 720675-74-1)
- 7-(4-Phenoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 320417-19-4)
- 4-Amino-1-(2-methoxyethyl)pyrrolidin-2-one (CAS 1015846-28-2)
- 2-Methyl-10-phenyl-2,3-dihydroimidazo[2,1-b]quinazolin-5(10H)-one (CAS 57247-52-6)
- 2-Amino-2-(3-fluoro-2-methylphenyl)acetic acid (CAS 1270316-45-4)
- 7-Methoxy-2,3-dihydrobenzofuran-3-acetic Acid (CAS 93198-73-3)
- 7-Amino-3-isopropyl-3,4-dihydroquinoxalin-2(1H)-one (CAS 860672-30-6)
- (αR,βR)-β-Phenyl Isoserine Hydrochloride (CAS 161453-08-3)
- 4-(4-Chloro-1h-pyrazol-1-yl)-2-(isopropylamino)butanoic acid (CAS 1342084-31-4)
- (2,4-Dimethylphenyl)iodo[tris(1,1-dimethylethyl)phosphine]palladium (CAS 668488-21-9)
- Dabrafenib Impurity 6 (CAS CATO-C4X-30336)
- Semaglutide impurity 55 (CAS CATO-C4X-222655)
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