sec-Butyl-[4-(4-chloro-phenyl)-3H-thiazol-2-ylidene]-amine CAS 571150-03-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including sec-Butyl-[4-(4-chloro-phenyl)-3H-thiazol-2-ylidene]-amine.

sec-Butyl-[4-(4-chloro-phenyl)-3H-thiazol-2-ylidene]-amine (CAS 571150-03-3), molecular formula C13H15ClN2S and molecular weight 266.79 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of sec-Butyl-[4-(4-chloro-phenyl)-3H-thiazol-2-ylidene]-amine (C13H15ClN2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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