| CAS No. | 57135-11-2 |
| Molecular Formula | C6H6N4S |
| Molecular Weight | 166.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 166.20 g/mol gives [1,3]thiazolo[5,4-b]pyridin-2-ylhydrazine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
[1,3]thiazolo[5,4-b]pyridin-2-ylhydrazine (CAS 57135-11-2), molecular formula C6H6N4S and molecular weight 166.20 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of [1,3]thiazolo[5,4-b]pyridin-2-ylhydrazine (C6H6N4S) is characterized by a nitrile group, sulfur-containing functionality, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), [1,3]thiazolo[5,4-b]pyridin-2-ylhydrazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C6H6N4S |
| Molecular Weight | 166.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |