1-(4-Fluorophenyl)naphthalene CAS 572-52-1
| CAS No. | 572-52-1 |
| Molecular Formula | C16H11F |
| Molecular Weight | 222.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-(4-Fluorophenyl)naphthalene (CAS 572-52-1) is a high-purity analytical reference standard with the molecular formula C16H11F and a molecular weight of 222.26 g/mol.
The molecular framework of 1-(4-Fluorophenyl)naphthalene (C16H11F) is characterized by fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 1-(4-Fluorophenyl)naphthalene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H11F |
| Molecular Weight | 222.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Fluorophenyl Standards
- N-(3-fluorophenyl)piperidine-4-carboxamide (CAS 1016532-14-1)
- 1-(2-Fluorophenyl)cyclohexanecarboxylic acid (CAS 106795-66-8)
- (E)-3-(4-fluorophenyl)-5-methylhex-2-enoic acid (CAS 1216362-44-5)
- 1-[(4-fluorophenyl)methyl]cyclopentane-1-carboxylic acid (CAS 1225506-32-0)
- 5-(4-Fluorophenyl)-1-propylpyrazolidin-3-one (CAS 131960-05-9)
- 5-(2-Fluorophenyl)piperidine-3-carboxamide (CAS 1421601-36-6)
- 5-(3-Fluorophenyl)piperidine-3-carboxamide (CAS 1421604-35-4)
- 1-(4-Fluorophenyl)-3,3-dimethylpiperazin-2-one (CAS 1514610-57-1)
Recommended Standards
- 1-(4-Fluorophenyl)cyclohexanecarboxylic Acid (CAS 214263-00-0)
- 1-(Furan-2-yl)-2-((furan-2-ylmethyl)thio)ethan-1-one (CAS 438482-00-9)
- 1-(4-Fluorophenyl)-2-(piperazin-1-yl)ethan-1-one (CAS 556807-81-9)
- 1,1-dioxo-[1,2,5]thiadiazolidine-2-carboxylic acid tert-butyl ester (CAS 263719-76-2)
- 5-Formyl-2-hydroxy-N,N-dimethylbenzamide (CAS 1243388-11-5)
- 2,3-Dichloro-4-fluorobenzenesulfonamide (CAS 1806302-21-5)
- N5,N5-Dimethyl-1H-pyrazole-3,5-diamine (CAS 935667-36-0)
- Methyl 2-fluoro-4-[4-fluoro-3-(methoxycarbonyl)phenyl]benzoate (CAS 1820614-91-2)
- 5-Ethyl-1,3-dimethyl-1H-pyrazolo[4,3-d]pyrimidin-7(4H)-one (CAS 89239-43-0)
- 3-Methyl-2-(prop-2-yn-1-ylthio)thieno[3,2-d]pyrimidin-4(3H)-one (CAS 338779-13-8)
- 2,6-Dimethylheptane-4-sulfonyl chloride (CAS 1250350-63-0)
- (3,3,3-Trifluoroprop-1-ene-1,1,2-triyl)tris(phenylsulfane) (CAS 34633-56-2)
- 2-Amino-2-(3,4-dimethylphenyl)propan-1-ol (CAS 1182889-37-7)
- D-[Phe]6-Liraglutide (CAS CATO-C4X-199235)
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