2-Chloro-biphenyl-4-ylamine CAS 5730-85-8
| CAS No. | 5730-85-8 |
| Molecular Formula | C12H10ClN |
| Molecular Weight | 203.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 203.67 g/mol gives 2-Chloro-biphenyl-4-ylamine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Chloro-biphenyl-4-ylamine (CAS 5730-85-8), molecular formula C12H10ClN and molecular weight 203.67 g/mol, is a CATO reference standard with documented purity and traceability.
2-Chloro-biphenyl-4-ylamine (C12H10ClN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Chloro-biphenyl-4-ylamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10ClN |
| Molecular Weight | 203.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-Chloro-N-phenylaniline (CAS 101-17-7)
- 4-chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbaldehyde (CAS 1111237-78-5)
- 2-Chloro-4-(4-methylphenyl)pyridine (CAS 1202574-24-0)
- 2'-Chloro-[1,1'-biphenyl]-2-amine (CAS 1203-43-6)
- 2'-Chloro-[1,1'-biphenyl]-4-amine (CAS 1204-42-8)
- 2-Chloro-4-methyl-5-phenylpyridine (CAS 1214335-53-1)
- 2-Chloro-3-methyl-4-phenylpyridine (CAS 1221719-00-1)
- 4-chloro-5,5-dimethyl-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one (CAS 1226804-02-9)
Recommended Standards
- 2-chloro-7-methyl-pyrrolo[2,3-d]pyrimidine-5-carbaldehyde (CAS 2092532-66-4)
- 3-(4-Chlorobenzyl)pyridine (CAS 93293-21-1)
- 2-Chloro-6-methyl-4-phenylpyridine (CAS 54453-92-8)
- 3-(5-Chloro-2-thienyl)pyridine (CAS 71637-31-5)
- 1-(1-Ethyl-1H-indol-3-yl)-3-(3-morpholinopropyl)urea (CAS 899990-75-1)
- 4-(3-Nitrophenyl)-1,4-dihydrobenzo[4,5]imidazo[1,2-a][1,3,5]triazin-2-amine (CAS 78650-05-2)
- N-(4-amino-2-fluorophenyl)-3-chlorobenzamide (CAS 1283396-12-2)
- 9-Ethyl-10-phenylanthracene (CAS 77539-21-0)
- 2-Hydroxyethyl benzoate (CAS 94-33-7)
- 6-Fluoro-N-(4-methoxyphenyl)quinolin-4-amine (CAS 1018041-95-6)
- 3-(5-cyclopropyl-1H-1,2,3,4-tetrazol-1-yl)-4-fluoroaniline (CAS 1248595-67-6)
- 5-Amino-1-Boc-3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl hydrochloride (CAS 1187930-40-0)
- Methyl 6-bromo-3-nitropicolinate (CAS 1805473-07-7)
- [Tyr15] Fibrinopeptide B, human (CAS 125455-56-3)
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