1,3-dioxan-2-ylmethanamine CAS 57366-83-3
| CAS No. | 57366-83-3 |
| Molecular Formula | C5H11NO2 |
| Molecular Weight | 117.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1,3-dioxan-2-ylmethanamine is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1,3-dioxan-2-ylmethanamine (CAS 57366-83-3), a certified reference material (molecular formula C5H11NO2, MW 117.15 g/mol) for analytical method development and quality control.
The molecular framework of 1,3-dioxan-2-ylmethanamine (C5H11NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1,3-dioxan-2-ylmethanamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H11NO2 |
| Molecular Weight | 117.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1973 |
| Nitrogen Atoms | 1 |
Related dioxan Standards
- [(2S)-1,4-Dioxan-2-yl]methanamine (CAS 1337470-52-6)
- [(2R)-1,4-Dioxan-2-yl]methanamine (CAS 1449010-18-7)
- (1,3-Dioxan-2-yl)methanol (CAS 39239-93-5)
- (1,3-Dioxan-4-yl)methanol (CAS 4728-06-7)
- 5-Methyl-1,3-dioxan-2-one (CAS 87831-99-0)
- 2-(1,4-Dioxan-2-yl)acetonitrile (CAS 1824433-84-2)
- 1-(1,4-Dioxan-2-yl)ethan-1-one (CAS 15957-23-0)
- 2-(1,3-Dioxan-2-yl)ethan-1-amine (CAS 118599-06-7)
Recommended Standards
- 1,3,6-dioxazocane (CAS 77738-97-7)
- 1,4-oxazepan-6-ol (CAS 933739-97-0)
- 1-(aminomethyl)cyclobutane-1,3-diol (CAS 2168557-86-4)
- 1-Amino-3-hydroxy-3-methylbutan-2-one (CAS 885032-38-2)
- 3-(Cyclopropyl(thieno[2,3-d]pyrimidin-4-yl)amino)propanenitrile (CAS 1271669-14-7)
- Tris(perfluorophenyl) 2,2',2''-nitrilotriacetate (CAS 371162-00-4)
- 1-benzofuran-4-ylmethanamine hydrochloride (CAS 1989659-35-9)
- methyl 3-amino-3-(naphthalen-2-yl)propanoate hydrochloride (CAS 133153-69-2)
- ([Ir(dF(CF3ppy)2)(5,5'-CF3-bpy)]PF6 (CAS 1973375-72-2)
- 1-Benzyl-4-methylpiperidin-3-amine dihydrochloride (CAS 2060045-13-6)
- Phenoxymethylpenicillin Impurity 18 (CAS CATO-C4X-212618)
- 1-(4-Chloro-2-fluorophenyl)-3-(2,4-dimethylphenyl)propan-1-one (CAS 898794-42-8)
- 4-Amino-6-(4-bromophenyl)-1,6-dihydro-1,3,5-triazine-2-thiol (CAS 1142208-33-0)
- Semaglutide impurity 27 (CAS CATO-C4X-222627)
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