8-Acetyl-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one CAS 57369-01-4

Purity 97%+In StockPharmaceutical Standards
CAS No.57369-01-4
Molecular FormulaC13H13NO2
Molecular Weight215.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

8-Acetyl-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one CAS 57369-01-4 chemical structure

Description

8-Acetyl-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one (CAS 57369-01-4), molecular formula C13H13NO2 and molecular weight 215.25 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 8-Acetyl-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one (C13H13NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 8-Acetyl-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H13NO2
Molecular Weight215.25 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1973
Nitrogen Atoms1

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