5-Bromo-2-chlorobenzonitrile CAS 57381-44-9
| CAS No. | 57381-44-9 |
| Molecular Formula | C7H3BrClN |
| Molecular Weight | 216.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Bromo-2-chlorobenzonitrile (CAS 57381-44-9) is a high-purity analytical reference standard with the molecular formula C7H3BrClN and a molecular weight of 216.46 g/mol.
5-Bromo-2-chlorobenzonitrile (C7H3BrClN) contains a nitrile group, chlorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Bromo-2-chlorobenzonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H3BrClN |
| Molecular Weight | 216.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 2-Bromo-3-chlorobenzonitrile (CAS 1031929-33-5)
- 3-Bromo-5-chloro-2-ethynylpyridine (CAS 1211528-84-5)
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- 5-Bromo-2-chloro-4-ethynylpyridine (CAS 1823919-38-5)
Recommended Standards
- 4-Bromo-3-chlorobenzonitrile (CAS 57418-97-0)
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