2-Bromo-4-chlorobenzonitrile CAS 57381-49-4
| CAS No. | 57381-49-4 |
| Molecular Formula | C7H3BrClN |
| Molecular Weight | 216.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Bromo-4-chlorobenzonitrile is closely related to a nitrile group, chlorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Bromo-4-chlorobenzonitrile (CAS 57381-49-4) is a high-purity analytical reference standard with the molecular formula C7H3BrClN and a molecular weight of 216.46 g/mol.
Structurally, 2-Bromo-4-chlorobenzonitrile (C7H3BrClN) contains a nitrile group, chlorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 216.46 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Bromo-4-chlorobenzonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H3BrClN |
| Molecular Weight | 216.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 2-Bromo-3-chlorobenzonitrile (CAS 1031929-33-5)
- 3-Bromo-5-chloro-2-ethynylpyridine (CAS 1211528-84-5)
- 4-Bromo-2-chloro-6-ethynylpyridine (CAS 1256789-66-8)
- 5-Bromo-2-chloro-3-ethynylpyridine (CAS 1256791-73-7)
- 3-Bromo-2-chloro-6-ethynylpyridine (CAS 1256808-39-5)
- 2-Bromo-4-chloro-6-ethynylpyridine (CAS 1256820-09-3)
- 4-Bromo-2-chlorobenzonitrile (CAS 154607-01-9)
- 5-Bromo-2-chloro-4-ethynylpyridine (CAS 1823919-38-5)
Recommended Standards
- 2-Bromo-5-chlorobenzonitrile (CAS 57381-37-0)
- 2-Bromo-6-chlorobenzonitrile (CAS 6575-08-2)
- 3-Bromo-2-chlorobenzonitrile (CAS 914250-82-1)
- 3-Bromo-4-chlorobenzonitrile (CAS 948549-53-9)
- 2-Methyl-6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine (CAS 1369224-98-5)
- (3R,6S)-1,6-Dimethylpiperidin-3-amine (CAS 1273565-20-0)
- 5-Phenyl-3-(phenylsulfonyl)isoxazole (CAS 72309-53-6)
- 4-(Trifluoromethyl)benzo[d][1,3]dioxol-2-one (CAS 933674-86-3)
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- 1-(3-chloro-5-fluoro-phenyl)hexahydropyrimidine-2,4-dione (CAS 1691633-40-5)
- 1-(prop-2-en-1-yl)cyclobutane-1-carboxylic acid (CAS 1193397-42-0)
- Trazodone Impurity 33 (CAS CATO-C4X-177233)
- Semaglutide impurity 48 (CAS CATO-C4X-222648)
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