Flecainide Acetate EP Impurity E CAS 57415-36-8
| CAS No. | 57415-36-8 |
| Molecular Formula | C17H14F6N2O3 |
| Molecular Weight | 408.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Flecainide Acetate EP Impurity E is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Flecainide Acetate EP Impurity E (CAS 57415-36-8) is a certified pharmaceutical impurity reference standard with the molecular formula C17H14F6N2O3 and a molecular weight of 408.30 g/mol.
Flecainide Acetate EP Impurity E (C17H14F6N2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Flecainide Acetate EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H14F6N2O3 |
| Molecular Weight | 408.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Flecainide Standards
Recommended Standards
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- 3-(6-chloro-2-methoxypyridin-3-yl)-3-methylpiperidin-2-one (CAS 1610563-78-4)
- Methyl 2-amino-3-(4-nitrophenyl)propionate (CAS 85317-52-8)
- 2-Amino-6-(difluoromethyl)-5-methoxypyridin-3-ol (CAS 1806815-12-2)
- 2,4-Dichloro-1H-indole-3-carbaldehyde (CAS 28035-67-8)
- 2-Bromo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine (CAS 1375302-65-0)
- (2-Cyano-4-(piperidin-1-yl)phenyl)boronic acid (CAS 2225178-31-2)
- Semaglutide-d5 (CAS CATO-C4X-2226153)
Why CATO?
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