2-(8-Hydroxyquinolin-5-yl)acetic acid CAS 57434-92-1

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(8-Hydroxyquinolin-5-yl)acetic acid.

2-(8-Hydroxyquinolin-5-yl)acetic acid (CAS 57434-92-1), molecular formula C11H9NO3 and molecular weight 203.19 g/mol, is a CATO reference standard with documented purity and traceability.

2-(8-Hydroxyquinolin-5-yl)acetic acid (C11H9NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(8-Hydroxyquinolin-5-yl)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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