Glutamic acid Impurity 4 CAS 57444-70-9
| CAS No. | 57444-70-9 |
| Molecular Formula | C12H12ClNO5 |
| Molecular Weight | 285.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Glutamic acid Impurity 4.
Glutamic acid Impurity 4 (CAS 57444-70-9) is a certified pharmaceutical impurity reference standard with the molecular formula C12H12ClNO5 and a molecular weight of 285.68 g/mol.
Structurally, Glutamic acid Impurity 4 (C12H12ClNO5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 285.68 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Glutamic acid Impurity 4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H12ClNO5 |
| Molecular Weight | 285.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Glutamic Standards
- Glutamic acid impurity 5 (CAS 87039-96-1)
- Glutamic acid impurity 6 (CAS 1308957-12-1)
- Glutamic acid impurity 7 (CAS CATO-C4X-28627)
- L-Glutamic acid, 4-(2-naphthalenylmethyl)-, (4R)- (CAS 207497-67-4)
- L-Glutamic acid γ-(3-carboxy-4-hydroxyanilide) (CAS 74929-17-2)
- L-Glutamic acid γ-(2,2,2-trichloroethyl) ester (CAS 92739-23-6)
- Glutamic acid Impurity 10 (CAS 67278-32-4)
- Glutamic acid impurity 8 (CAS 67278-37-9)
Recommended Standards
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- Indacaterol Impurity 56 HCl (CAS CATO-C4X-150056)
- tert-Butyl 4-oxo-4,5-dihydrofuro[2,3-c]pyridine-6(7H)-carboxylate (CAS 478625-47-7)
- 2-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine dihydrochloride (CAS 1609395-81-4)
- 474707-24-9 6-bromanyl-4-piperazin-1-yl-quinoline 6-bromo-4-(1-piperazinyl)quinoline A827235 (CAS 474707-24-9)
- Ethyl 5-bromo-1-(2-nitrophenyl)-1h-pyrazole-4-carboxylate (CAS 1245227-21-7)
- Tributyl Phosphite (CAS 102-85-2)
- 4-{[(E)-(4-Methoxyphenyl)methylidene]amino}benzoic Acid (CAS 4380-38-5)
- Tirzepatide Impurity 33 (CAS CATO-C4X-324033)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com