6-Bromo-3-(pyridin-2-yl)-1H-indazole CAS 574758-37-5
| CAS No. | 574758-37-5 |
| Molecular Formula | C12H8BrN3 |
| Molecular Weight | 274.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 6-Bromo-3-(pyridin-2-yl)-1H-indazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
6-Bromo-3-(pyridin-2-yl)-1H-indazole (CAS 574758-37-5) is a high-purity analytical reference standard with the molecular formula C12H8BrN3 and a molecular weight of 274.12 g/mol.
The molecular framework of 6-Bromo-3-(pyridin-2-yl)-1H-indazole (C12H8BrN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H8BrN3 |
| Molecular Weight | 274.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
- 7-Bromo-3-phenyl-[1,2,4]triazolo[4,3-a]pyridine (CAS 1021923-08-9)
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- 6-Bromo-8-phenyl-[1,2,4]triazolo[4,3-a]pyridine (CAS 1202277-96-0)
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- 5-bromo-2-(pyridin-2-yl)-1H-1,3-benzodiazole (CAS 1304458-60-3)
- 2-Bromo-7-phenyl-5H-pyrrolo[2,3-b]pyrazine (CAS 1347977-06-3)
- 7-Bromo-2-phenyl-[1,2,4]triazolo[1,5-a]pyridine (CAS 1380331-12-3)
Recommended Standards
- 6-Bromo-2-phenylimidazo[1,2-a]pyrimidine (CAS 355398-02-6)
- 6-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazolo[1,5-a]pyridine (CAS 2435579-38-5)
- 6-Bromo-2-phenyl-1H-imidazo[4,5-b]pyridine (CAS 65147-89-9)
- 6-Methoxy-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indazole (CAS 2243949-54-2)
- (R)-tert-Butyl 2-(2-methoxy-2-oxoethyl)pyrrolidine-1-carboxylate (CAS 132482-05-4)
- (R)-N-(1-(3-(8-methyl-5-(methylamino)-8H-imidazo[4,5-d]thiazolo[5,4-b]pyridin-2-yl)phenyl)ethyl)-2-([3H] methyl)sulfonyl)benzamide (CAS 1609393-85-2)
- 2-(2-Fluoro-3-(trifluoromethyl)phenyl)acetic acid (CAS 194943-83-4)
- 3-(Benzenesulfonyl)-4,6-dimethylpyridin-2-yl 2,4,6-trichlorobenzoate (CAS 400082-20-4)
- 4-(P-tolyl)-1H-pyrrole-3-carboxylic acid (CAS 191668-22-1)
- (2R,6R)-4-Boc-2-(hydroxymethyl)-6-methylmorpholine (CAS 1700609-48-8)
- 5-(1,3-Dimethyl-1H-pyrazol-5-yl)-6-hydroxy-1,3-dimethylpyrimidine-2,4(1H,3H)-dione (CAS 400074-62-6)
- (βR)-β-Amino-3-chloro-4,5-dihydro-5-isoxazoleethanol (Mixture of Diastereomers) (CAS 1322622-94-5)
- 3,4-Dihydro-6-methoxy-7-(phenylmethoxy)-1-[[4-(phenylmethoxy)phenyl]methyl]-isoquinoline (CAS 500577-65-1)
- Semaglutide Impurity 137 (x TFA Salt) (CAS CATO-C4X-2226137)
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