7-Hydroxy-4-(trifluoromethyl)coumarin CAS 575-03-1
| CAS No. | 575-03-1 |
| Molecular Formula | C10H5F3O3 |
| Molecular Weight | 230.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 7-Hydroxy-4-(trifluoromethyl)coumarin meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
7-Hydroxy-4-(trifluoromethyl)coumarin (CAS 575-03-1), molecular formula C10H5F3O3 and molecular weight 230.14 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C10H5F3O3, 7-Hydroxy-4-(trifluoromethyl)coumarin contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 230.14 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H5F3O3 |
| Molecular Weight | 230.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Hydroxy Standards
- 4-Hydroxy-7-(trifluoromethoxy)quinazoline (CAS 1260759-77-0)
- 2-Hydroxy-9-(trifluoromethyl)-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 1365987-38-7)
- 4-Hydroxy-6-(trifluoromethyl)-2H-chromen-2-one (CAS 1517131-31-5)
- 4-Hydroxy-8-(trifluoromethyl)-2H-chromen-2-one (CAS 1539002-96-4)
- 7-Hydroxy-2-(trifluoromethyl)-4H-chromen-4-one (CAS 172739-50-3)
- 2-Hydroxy-4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzaldehyde (CAS 308085-25-8)
- 8-Hydroxy-2-(trifluoromethyl)-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 2648773-63-9)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen piperazin-2-ylboronate (CAS 2223006-88-8)
Recommended Standards
- 299405-25-7 (5-Methyl-3,4-dinitro-1H-pyrazol-1-yl)acetic acid MFCD00682554 (CAS 299405-25-7)
- 5-[2-(Trifluoromethoxy)phenyl]-2H-tetrazole (CAS 1261268-92-1)
- N-[1,2- (CAS 478529-44-1)
- Triisobutyl borate (CAS 13195-76-1)
- (3-Chloro-5-fluorophenyl)(thiophen-3-yl)methanol (CAS 1443314-29-1)
- (Z)-5-(2,5-Dimethoxybenzylidene)thiazolidine-2,4-dione (CAS 154617-50-2)
- 2-(benzylamino)-5-chloropyrimidine-4-carboxylic acid (CAS 522627-72-1)
- 1-ACetyl-4-piperidin-4-ylpiperazine dihydrochloride (CAS 2108457-88-9)
- 4-Chloro-N-[1-(5-{[(3,4-dichlorophenyl)methyl]sulfanyl}-4-methyl-4H-1,2,4-triazol-3-yl)-2-phenylethyl]benzene-1-sulfonamide (CAS 338794-28-8)
- H-Gly-Gly-Glu-Ala-OH (H-3340.0250) (CAS 68171-98-2)
- Ethyl 2-((3-hydroxyphenyl)sulfonyl)-2-methylpropanoate (CAS 2113411-01-9)
- 3-Bromo-2,6-difluorophenylboronic Acid (CAS 352535-84-3)
- N-Methyl-4-(trifluoromethoxy)aniline (CAS 41419-59-4)
- Liraglutide (CAS 204656-20-2)
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