Dexmedetomidine Impurity 23 CAS 57527-74-9
| CAS No. | 57527-74-9 |
| Molecular Formula | C10H13Cl |
| Molecular Weight | 168.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Dexmedetomidine Impurity 23 (CAS 57527-74-9) is a certified pharmaceutical impurity reference standard with the molecular formula C10H13Cl and a molecular weight of 168.66 g/mol.
The molecular framework of Dexmedetomidine Impurity 23 (C10H13Cl) is characterized by chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Dexmedetomidine Impurity 23 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H13Cl |
| Molecular Weight | 168.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl-containing |
Related Dexmedetomidine Standards
- Dexmedetomidine Impurity 13 (CAS 104245-83-2)
- Dexmedetomidine Impurity 16 (CAS 60907-88-2)
- Dexmedetomidine Impurity 40 (CAS 881409-85-4)
- Dexmedetomidine Impurity 21 (CAS 2514763-84-7)
- Dexmedetomidine Impurity 27 (CAS 78162-58-0)
- Dexmedetomidine Impurity 74 (CAS CATO-C4X-123074)
- Dexmedetomidine Impurity 58 (CAS 104175-24-8)
- Dexmedetomidine Impurity 69 (CAS CATO-C4X-123069)
Recommended Standards
- (2-Chloroethyl)dimethoxy(methyl)silane (CAS 13508-51-5)
- (((Chloromethyl)thio)methyl)trimethylsilane (CAS 105850-89-3)
- Medetomidine Impurity 82 (CAS 51270-91-8)
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- Benidipine Impurity 26 (CAS CATO-C4X-112026)
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