(2-Chloro-5-fluoropyrimidin-4-yl)-(3,4-dichlorophenyl)amine CAS 575473-57-3
| CAS No. | 575473-57-3 |
| Molecular Formula | C10H5Cl3FN3 |
| Molecular Weight | 292.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 292.52 g/mol gives (2-Chloro-5-fluoropyrimidin-4-yl)-(3,4-dichlorophenyl)amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(2-Chloro-5-fluoropyrimidin-4-yl)-(3,4-dichlorophenyl)amine (CAS 575473-57-3), molecular formula C10H5Cl3FN3 and molecular weight 292.52 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2-Chloro-5-fluoropyrimidin-4-yl)-(3,4-dichlorophenyl)amine (C10H5Cl3FN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (2-Chloro-5-fluoropyrimidin-4-yl)-(3,4-dichlorophenyl)amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H5Cl3FN3 |
| Molecular Weight | 292.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- (4-Chloro-3-((4-methoxybenzyl)oxy)phenyl)boronic acid (CAS 1180743-50-3)
- (3-Chloro-4-((4-methoxybenzyl)oxy)phenyl)boronic acid (CAS 870777-25-6)
- 2-(2-Chloro-6-methoxyphenyl)-6-methoxyphenylboronic acid (CAS 2377607-94-6)
- 4-Chloro-2-(4-methoxybenzyloxy)phenylboronic acid (CAS 2377611-82-8)
- 5-Chloro-2-(3,5-dichlorophenyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1707584-33-5)
- 5-Chloro-2-(3,4-dichlorophenyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1707727-50-1)
- 5-Chloro-2-(2,4-dichlorophenyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1779119-79-7)
- 5-Chloro-3-iodo-6-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1000340-16-8)
Recommended Standards
- N-Acetyl-N-(5-bromo-2-chloropyrimidin-4-yl)acetamide (CAS 1630906-79-4)
- α-Linolenic Acid-D14 (CAS 1622944-40-4)
- (4-(Benzyloxy)-3-chloro-5-methoxyphenyl)boronic acid (CAS 1218790-59-0)
- 3-Bromo-1-(4-chloro-3-fluorophenyl)pyrrolidin-2-one (CAS 1339032-58-4)
- 2-Bromoethylchloroformate (CAS 4801-27-8)
- 6-((2,2-Diphenylethyl)amino)-9-(tetrahydro-2H-pyran-2-yl)-9H-purine-2-carbonitrile (CAS 264608-17-5)
- 2-(2-Amino-4-iodophenyl)acetic acid (CAS 1261861-32-8)
- Fmoc-Lys (biotin-PEG4)-OH (CAS 1334172-64-3)
- 2-(4-Bromo-1H-pyrazol-1-yl)acetonitrile (CAS 925224-08-4)
- 4-(3-Methoxypropyl)-4h-1,2,4-triazole-3-thiol (CAS 75028-28-3)
- Methyl 6-cyano-1H-indole-3-carboxylate (CAS 1357147-38-6)
- 3-Vinyltetrahydro-2h-pyran (CAS 1343450-99-6)
- 4-Chloro-1-(triisopropylsilyl)pyrrolo[2,3-b]pyridine (CAS 651744-48-8)
- Uremic Pentapeptide (CAS 71494-20-7)
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