2-(3-Chlorobenzamido)acetic acid CAS 57728-59-3
| CAS No. | 57728-59-3 |
| Molecular Formula | C9H8ClNO3 |
| Molecular Weight | 213.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 213.62 g/mol gives 2-(3-Chlorobenzamido)acetic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(3-Chlorobenzamido)acetic acid (CAS 57728-59-3), molecular formula C9H8ClNO3 and molecular weight 213.62 g/mol, is a CATO reference standard with documented purity and traceability.
2-(3-Chlorobenzamido)acetic acid (C9H8ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(3-Chlorobenzamido)acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H8ClNO3 |
| Molecular Weight | 213.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorobenzamido Standards
- 2-(4-Chlorobenzamido)acetic acid (CAS 13450-77-6)
- 2-(2-Chlorobenzamido)acetic acid (CAS 16555-60-5)
- 3-(3-Chlorobenzamido)-2-methylpropanoic acid (CAS 1211469-63-4)
- 2-(2-Chlorobenzamido)-3-hydroxybutanoic acid (CAS 1008206-36-7)
- 5-(2-Chlorobenzamido)-1H-pyrazole-3-carboxylic acid (CAS 957134-36-0)
- 1-(4-Chlorobenzamido)cyclopentane-1-carboxylic acid (CAS 15026-82-1)
- (S)-2-(2-chlorobenzamido)hexanoic acid (CAS 1396969-08-6)
- 2-(4-Chlorobenzamido)hexanoic acid (CAS 34337-17-2)
Recommended Standards
- Sodium 6-amino-5-chloro-2-cyclopropylpyrimidine-4-carboxylate (CAS 858955-50-7)
- Prucalopride Impurity 23 (CAS 123654-26-2)
- N-(Benzo[d][1,3]dioxol-5-yl)-2-chloroacetamide (CAS 227199-07-7)
- Opicapone impurity 31 (CAS CATO-C4X-240431)
- 3-Oxopiperidine-4-carbonitrile (CAS 1378793-22-6)
- n-(4-(Pyrrolidin-1-yl)benzyl)ethanamine (CAS 1095224-25-1)
- 1-Azabicyclo[2.2.1]heptane-2-carboxylic acid (CAS 1314897-64-7)
- 4-[1-(1-Ethoxyethyl)-1H-pyrazol-4-yl]-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-c]pyridazine (CAS 1269822-91-4)
- 4-(4H-1,2,4-Triazol-4-yl)phenol (CAS 98581-86-3)
- Methyl 2-((3-ethyl-5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetate (CAS 577762-51-7)
- n,2,4,6-Tetramethylbenzene-1-sulfonamide (CAS 106003-69-4)
- 5-Bromo-4-methyl-2-(2-methylpiperidin-1-yl)pyridine (CAS 1220028-97-6)
- tributyl-(6-ethoxypyrazin-2-yl)stannane (CAS 1224436-45-6)
- Peptide 434 (CAS CATO-CPTD788434)
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