4-((2-Bromobenzylidene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione CAS 577763-98-5
| CAS No. | 577763-98-5 |
| Molecular Formula | C15H10BrFN4S |
| Molecular Weight | 377.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-((2-Bromobenzylidene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione.
4-((2-Bromobenzylidene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 577763-98-5), molecular formula C15H10BrFN4S and molecular weight 377.23 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/bromine substitution, 4-((2-Bromobenzylidene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 377.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-((2-Bromobenzylidene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H10BrFN4S |
| Molecular Weight | 377.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Bromobenzylidene Standards
- 4-((3-Bromobenzylidene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 676245-22-0)
- 4-((3-Bromobenzylidene)amino)-3-(4-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 577996-32-8)
- 4-((4-Bromobenzylidene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 573973-61-2)
- 4-((4-Bromobenzylidene)amino)-3-(4-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 675835-02-6)
- 3-((3-Bromobenzylidene)amino)-2,5,6-trimethylthieno[2,3-d]pyrimidin-4(3H)-one (CAS 333341-31-4)
- 4-((2-Bromobenzylidene)amino)-3-(m-tolyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478255-87-7)
- 4-((3-Bromobenzylidene)amino)-3-(m-tolyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478255-50-4)
- 4-((4-Bromobenzylidene)amino)-3-(m-tolyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478256-00-7)
Recommended Standards
- 3-((4-Bromobenzyl)oxy)pyrido[1,2-a]indole-10-carbonitrile (CAS 338981-96-7)
- 2-Amino-4-(4-bromophenyl)-4H-benzo[h]chromene-3-carbonitrile (CAS 860787-48-0)
- 2-([1,1'-Biphenyl]-4-yl)-6-bromoimidazo[1,2-a]pyridine-3-carbaldehyde (CAS 727652-14-4)
- 1-(4-Bromo-2-fluorophenyl)-3-(quinoxalin-6-yl)thiourea (CAS 478079-13-9)
- [4-(4-Amino-phenyl)-piperazin-1-yl]-(2-fluoro-phenyl)-methanone (CAS 758699-84-2)
- N-(tert-butyl)-3-methyl-5-vinylpyridin-2-amine (CAS 1355206-86-8)
- 4'-Fluoro-2,3',4-tribromodiphenyl ether (CAS 863314-85-6)
- Disodium folinate (CAS 163254-40-8)
- Fluorinert FC-40 (CAS 51142-49-5)
- All-rac-alfa-Tocopherol EP Impurity C (Mixture of Isomers) (CAS CATO-C4X-119519)
- 2-Chloro-N-{3-cyano-4-[(2-methylphenyl)sulfanyl]phenyl}benzamide (CAS 306980-74-5)
- Methyl 6-amino-5-methoxypyrazine-2-carboxylate (CAS 566205-86-5)
- 5-Bromo-2-methyl-3,4-dihydroisoquinolin-1(2H)-one (CAS 1100509-38-3)
- Semaglutide-d5 (CAS CATO-C4X-2226153)
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