4'-Chloro-3'-fluoro-[1,1'-biphenyl]-2-amine CAS 577794-36-6
| CAS No. | 577794-36-6 |
| Molecular Formula | C12H9ClFN |
| Molecular Weight | 221.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4'-Chloro-3'-fluoro-[1,1'-biphenyl]-2-amine.
4'-Chloro-3'-fluoro-[1,1'-biphenyl]-2-amine (CAS 577794-36-6) is a high-purity analytical reference standard with the molecular formula C12H9ClFN and a molecular weight of 221.66 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, 4'-Chloro-3'-fluoro-[1,1'-biphenyl]-2-amine is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 221.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4'-Chloro-3'-fluoro-[1,1'-biphenyl]-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H9ClFN |
| Molecular Weight | 221.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- methyl 4-chloro-2-ethoxy-1,3-thiazole-5-carboxylate (CAS 1183408-06-1)
- 3-Chloro-4-fluorobiphenyl-3-amine (CAS 1226001-94-0)
- 2-Chloro-4-fluorobiphenyl-3-amine (CAS 1226002-02-3)
- 4-Chloro-4-fluorobiphenyl-3-amine (CAS 1226144-94-0)
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Recommended Standards
- 4-chloro-2-methoxybenzene-1-sulfonamide (CAS 749253-52-9)
- 4'-Chloro-3'-fluoro-[1,1'-biphenyl]-4-amine (CAS 863921-61-3)
- 4-(3-Chloro-4-fluorophenyl)aniline (CAS 405058-02-8)
- 4-chloro-6-fluoro-1H-indole-2-carboxylic acid (CAS 383133-62-8)
- 1-(2-Chloroacetyl)pyrazolidin-3-one (CAS 205829-17-0)
- 3-fluoro-7-methyl-imidazo[1,2-a]pyridine-2-carboxylic acid (CAS 696632-07-2)
- 1-(5-Amino-2-chlorobenzoyl)imidazolidin-2-one (CAS 1420792-12-6)
- (8-chloro-2,3-dihydro-1,4-benzodioxin-6-yl)methanamine (CAS 923215-34-3)
- Octahydro-2H-pyrido[1,2-a]pyrazine-8-carboxylic acid (CAS 1896912-85-8)
- 4-[2-(4-Bromo-2-methylphenoxy)ethyl]piperidinehydrochloride (CAS 1220016-72-7)
- 2-{2-[(4-carboxypyridin-2-yl)oxy]ethoxy}pyridine-4-carboxylic acid (CAS 1384430-54-9)
- 1-Bromo-4-chloro-2-(2-methoxyethoxy)benzene (CAS 1245563-20-5)
- (4-(Isoquinolin-4-yl)phenyl)methanamine (CAS 1484841-44-2)
- Ac, Gastrin Releasing Peptide (20-27), porcine (CAS 77714-20-6)
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