2-Chloro-6,8-difluoroquinoline CAS 577967-70-5
| CAS No. | 577967-70-5 |
| Molecular Formula | C9H4ClF2N |
| Molecular Weight | 199.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Chloro-6,8-difluoroquinoline is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-Chloro-6,8-difluoroquinoline (CAS 577967-70-5), a certified reference material (molecular formula C9H4ClF2N, MW 199.58 g/mol) for analytical method development and quality control.
Based on its molecular formula C9H4ClF2N, 2-Chloro-6,8-difluoroquinoline contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 199.58 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-6,8-difluoroquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H4ClF2N |
| Molecular Weight | 199.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-Chloro-3-(2,4-difluorophenyl)prop-2-enenitrile (CAS 1094390-29-0)
- 2-Chloro-5,7-difluoroquinoline (CAS 1188002-20-1)
- 4-Chloro-7,8-difluoroquinoline (CAS 1189105-64-3)
- 4-Chloro-5,8-difluoroquinoline (CAS 1208626-68-9)
- 2-Chloro-2,2-Difluoro-1-(4-Morpholinyl)Ethanone (CAS 121412-23-5)
- 2-Chloro-7,8-difluoroquinoline (CAS 1339595-32-2)
- 1-Chloro-6,7-difluoroisoquinoline (CAS 1602501-66-5)
- 3-Chloro-6,7-difluoroisoquinoline (CAS 1699360-37-6)
Recommended Standards
- 2-Chloro-5,8-difluoroquinoline (CAS 773148-82-6)
- 4-Chloro-5,7-difluoroquinoline (CAS 874831-46-6)
- 4-Chloro-6,7-difluoroquinoline (CAS 863785-94-8)
- 4-Chloro-6,8-difluoroquinoline (CAS 239463-89-9)
- N-(3-Cyclopropoxy-4-isopropylpyridin-2-yl)methanesulfonamide (CAS 1243468-07-6)
- (S)-2-Amino-3,3,3-trifluoro-2-methylpropan-1-ol (CAS 1390706-29-2)
- 4-((Tetrahydrofuran-2-yl)methoxy)aniline hydrochloride (CAS 1172071-34-9)
- 2-(3-cyanophenyl)propanoic acid (CAS 1249725-52-7)
- 7-Oxo-5,6,7,8-tetrahydro-1,8-naphthyridine-3-carbaldehyde (CAS 443956-57-8)
- 1,3-Dioxane-2-carbaldehyde (CAS 61960-29-0)
- N,N'-Dimethyl-N-(1,3,4-thiadiazol-2-yl)methanediamine (CAS 53532-26-6)
- Ethyl 1-allyl-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylate (CAS 82360-75-6)
- N-[[Methyl(1-methylethyl)amino]sulfonyl]-carbamic Acid 1,1-Dimethylethyl Ester (CAS 958002-25-0)
- Insulin Degludec impurity 4 (CAS CATO-C4X-21574)
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