2-((4-Ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-fluorophenyl)acetamide CAS 577997-33-2
| CAS No. | 577997-33-2 |
| Molecular Formula | C17H16FN5OS |
| Molecular Weight | 357.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-((4-Ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-fluorophenyl)acetamide (CAS 577997-33-2) is a high-purity analytical reference standard with the molecular formula C17H16FN5OS and a molecular weight of 357.41 g/mol.
The molecular framework of 2-((4-Ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-fluorophenyl)acetamide (C17H16FN5OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H16FN5OS |
| Molecular Weight | 357.41 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Ethyl Standards
- 2-((4-Ethyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-fluorophenyl)acetamide (CAS 585564-16-5)
- 2-((4-Ethyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-fluorophenyl)acetamide (CAS 618414-41-8)
- 2-((4-Ethyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-fluorophenyl)acetamide (CAS 578721-96-7)
- 2-((4-Ethyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-fluorophenyl)acetamide (CAS 557065-87-9)
- 2-((4-Ethyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-fluorophenyl)acetamide (CAS 557065-83-5)
- 2-((4-Ethyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-fluorophenyl)acetamide (CAS 483327-14-6)
- 2-((4-Ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-fluorophenyl)acetamide (CAS 482639-92-9)
- 3-[3,5-Bis(pyridin-2-yl)-4H-1,2,4-triazol-4-yl]-1-phenylurea (CAS 320418-24-4)
Recommended Standards
- 2-(4-Methoxyphenyl)-5-(pyridin-4-yl)-1,10b-dihydro-5H-benzo[e]pyrazolo[1,5-c][1,3]oxazine (CAS 303060-83-5)
- 3-(3-Methylphenyl)-N-(naphthalen-1-yl)-2-(2H-1,2,3,4-tetrazol-5-yl)propanamide (CAS 483994-01-0)
- 3,5-Bis(4-methoxyphenyl)-4-phenyl-4H-1,2,4-triazole (CAS 84833-18-1)
- 3-Methyl-4-((2-(4-methylquinolin-2-yl)hydrazineylidene)methyl)-1-phenyl-1H-pyrazol-5-ol (CAS 304683-42-9)
- 4-Morpholinopyrimidine-2-carboxylic acid (CAS 1557920-92-9)
- 4-(3,5-Bis(trifluoromethyl)phenyl)-4-hydroxycyclohexanone (CAS 1951441-45-4)
- 4-Bromo-n'-hydroxythiophene-2-carboximidamide (CAS 1094456-19-5)
- 7-Methyl-2-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidin-4(3H)-one (CAS 1707585-64-5)
- 2-(Thiophen-2-yl)quinoline (CAS 34243-33-9)
- 2-Amino-6-(bromomethyl)-4-(difluoromethyl)pyridin-3-ol (CAS 1806816-01-2)
- (Z)-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}(1-phenylethylidene)amine (CAS 326808-43-9)
- 3-(Cyclopropylmethoxy)-2-(trifluoromethyl)phenol (CAS 1243463-02-6)
- 3-(4-Benzylphenoxy)piperidine 4017AF 946681-24-9 C18H21NO (CAS 946681-24-9)
- Serpent Peptide 2AcOH (CAS 823202-99-9(free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com