1-Iodo-8-methoxynaphthalene CAS 5783-59-5
| CAS No. | 5783-59-5 |
| Molecular Formula | C11H9IO |
| Molecular Weight | 284.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-Iodo-8-methoxynaphthalene is closely related to a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-Iodo-8-methoxynaphthalene (CAS 5783-59-5) is a high-purity analytical reference standard with the molecular formula C11H9IO and a molecular weight of 284.09 g/mol.
Owing to a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system, 1-Iodo-8-methoxynaphthalene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 284.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H9IO |
| Molecular Weight | 284.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | I-containing |
Related Iodo Standards
- 1-Iodo-2-methoxynaphthalene (CAS 32721-21-4)
- 1-Iodo-3-methoxynaphthalene (CAS 691364-59-7)
- 1-Iodo-4-methoxynaphthalene (CAS 2607-25-2)
- 1-Iodo-5-methoxynaphthalene (CAS 61735-51-1)
- 1-Iodo-6-methoxynaphthalene (CAS 63469-49-8)
- 1-Iodo-7-methoxynaphthalene (CAS 66240-21-9)
- 2-Iodo-3-methoxynaphthalene (CAS 795278-91-0)
- 2-iodo-4-methoxy-benzoic acid (CAS 54435-09-5)
Recommended Standards
- 1-Iodonaphthalene-2-methanol (CAS 213991-84-5)
- 2-(2,4-Dichlorophenoxy)pyridine-3-carboxylic acid (CAS 36701-91-4)
- 2,4’-Dichloro-4-nitrodiphenyl Ether (CAS 22544-07-6)
- 2,4-Diamino-6-(4-bromo-2-fluorophenyl)-1,3,5-triazine (CAS 886762-47-6)
- N,α-Diethylphenethylamine HCl (CAS 29805-52-5)
- 3-Amino-4-(dimethylamino)-N,N-dimethylbenzamide (CAS 1158608-89-9)
- 1-(4-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-1,2,3-triazol-1-yl)phenyl)ethan-1-one (CAS 478041-19-9)
- 1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide (CAS 1192243-01-8)
- 1-((Chloromethyl)sulfonyl)-N,N-dimethylpiperidin-3-amine (CAS 1497266-32-6)
- 2-Methoxy-5-methylcyclohexa-2,5-diene-1,4-dione (CAS 614-13-1)
- N-(4-Bromo-3-methylphenyl)-3-(4-(methylthio)phenyl)acrylamide (CAS 478258-02-5)
- 4-Bromo-5-fluoro-2-methoxybenzoic acid (CAS 1780187-45-2)
- 5-Methoxy-1H-indol-4-ol (CAS 49635-16-7)
- Hexapeptide-10 (CAS 146439-94-3)
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