6-Hydroxyquinoline CAS 580-16-5
| CAS No. | 580-16-5 |
| Molecular Formula | C9H7NO |
| Molecular Weight | 145.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Hydroxyquinoline.
6-Hydroxyquinoline (CAS 580-16-5) is a high-purity analytical reference standard with the molecular formula C9H7NO and a molecular weight of 145.16 g/mol.
The molecular framework of 6-Hydroxyquinoline (C9H7NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Hydroxyquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H7NO |
| Molecular Weight | 145.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Hydroxyquinoline Standards
- 4-Hydroxyquinoline (CAS 611-36-9)
- 2-Hydroxyquinoline (CAS 59-31-4)
- 8-Hydroxyquinoline (CAS 148-24-3)
- 578-67-6 5-Hydroxyquinoline Quinolin-5-ol 5-21-03-00240 (Beilstein Handbook Reference) BRN 0114514 CCRIS 4330 EINECS 209-428-4 NSC 405729 (CAS 578-67-6)
- 3-Methyl-8-hydroxyquinoline (CAS 75457-13-5)
- 4-Methyl-8-hydroxyquinoline (CAS 3846-73-9)
- 3-Hydroxyquinoline 1-oxide (CAS 59953-98-9)
- 6-Hydroxyquinoline 1-Oxide (CAS 93499-73-1)
Recommended Standards
- X78B5D12FN 5424-01-1 3-Aminopyrazine-2-carboxylic acid Pyrazinecarboxylic acid, 3-amino- AI3-61137 EINECS 226-558-7 NSC 13148 NSC 225114 EC 226-558-7 UNII-X78B5D12FN (CAS 5424-01-1)
- 3-Oxo-3-phenylpropanenitrile (CAS 614-16-4)
- 52386-29-5 6-Amino-4-hydroxy-2-methoxypyrimidine,6-Amino-2-methoxy-4(1H)-pyrimidinone (CAS 52386-29-5)
- 2-methyl-oxazole-4-carboxylic acid methyl ester 2-methyl-oxazole-4-carboxylic aicd methyl ester 4-methyl-3,5-oxazolecarboxylic acid methyl ester 4-oxazolecarboxylic acid, 2-methyl-, methyl ester 4-oxazolecarboxylicacid,2-methyl-,methylester(9ci) 85806-67-3 Methyl 2-methyloxazole-4-carboxylate methyl 2-methyl-1,3-oxazole-4-carboxylate methyl-4-methyl-3,5-oxazolecarboxylate (CAS 85806-67-3)
- 7-Chloro-2,5-dimethyl-3-(m-tolyl)pyrazolo[1,5-a]pyrimidine (CAS 1204297-77-7)
- 4-Bromo-2-(chloromethyl)pyridine hydrochloride (CAS 1001414-94-3)
- 1,1,1,2,3,3,4,4,5,5,6,6,7,7,8,8-Hexadecafluoro-8-iodo-2-(trifluoromethyl)octane (CAS 865-77-0)
- 2-Chloroacetohydrazide hydrochloride (CAS 868-83-7)
- Methyl 2-((5-bromo-4-hydroxypyrimidin-2-yl)thio)acetate (CAS 1000018-61-0)
- Clarithromycin Impurity 22 (CAS CATO-C4X-100222)
- 2-(5-(Benzyloxy)-2-methyl-1H-indol-3-yl)ethanamine (CAS 18658-09-8)
- 6,7-Dimethoxy-3-(4-methoxybenzyl)-2-((2-methylbenzyl)thio)quinazolin-4(3H)-imine (CAS 477848-73-0)
- Methyl 3-(2,4-dimethoxyphenyl)-1H-pyrazole-5-carboxylate (CAS 890624-62-1)
- 149471-11-4 Neuropeptide DF2 L-Phenylalaninamide, L-alpha-aspartyl-L-arginyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-arginyl- Asp-arg-asn-phe-leu-arg-phe-NH2 Aspartyl-arginyl-asparaginyl-phenylalanyl-leucyl-arginyl-phenylalaninamide L-alpha-Aspartyl-L-arginyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-arginyl-L-phenylalaninamide DF(2) Neuropeptide Drnflrfamide (CAS 149471-11-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com