2-chloro-4,5,6,7-tetrahydro-1-benzothiophen-4-amine CAS 58095-48-0
| CAS No. | 58095-48-0 |
| Molecular Formula | C8H10ClNS |
| Molecular Weight | 187.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-chloro-4,5,6,7-tetrahydro-1-benzothiophen-4-amine (CAS 58095-48-0) is a high-purity analytical reference standard with the molecular formula C8H10ClNS and a molecular weight of 187.69 g/mol.
The molecular framework of 2-chloro-4,5,6,7-tetrahydro-1-benzothiophen-4-amine (C8H10ClNS) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 2-chloro-4,5,6,7-tetrahydro-1-benzothiophen-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10ClNS |
| Molecular Weight | 187.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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- Dichlorobis(tetrahydrofuran)zinc (CAS 24640-76-4)
- 5-(4-Fluorobenzyl)-2-(piperidin-3-yl)oxazole (CAS 1785759-46-7)
- 1-Benzyl-1h-indole-3-carbaldehyde (CAS 10511-51-0)
- 3’,5’,6’,7’-tetrahydrospiro[cyclobutane-1,4’-imidazo[4,5-c]pyridine] (CAS 1909313-05-8)
- N-(4-Dodecanamidophenyl)furan-2-carboxamide (CAS 337505-74-5)
- 2,3-Dibromo-5-fluoroanisole (CAS 1805122-29-5)
- Semaglutide impurity 75 (CAS CATO-C4X-222675)
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