Sevoflurane Impurity 6 CAS 58109-33-4
| CAS No. | 58109-33-4 |
| Molecular Formula | C5H6F6O2 |
| Molecular Weight | 212.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Sevoflurane Impurity 6 is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Sevoflurane Impurity 6 (CAS 58109-33-4, C5H6F6O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Sevoflurane Impurity 6 (C5H6F6O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 0.0, corresponding to approximately 0 ring(s) or double-bond equivalent(s). With a molecular weight of 212.09 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H6F6O2 |
| Molecular Weight | 212.09 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | F-containing |
Related Sevoflurane Standards
- Sevoflurane Impurity 6 (CAS 26103-07-1)
- Sevoflurane (CAS 28523-86-6)
- Sevoflurane Impurity 12 (CAS 206756-25-4)
- Sevoflurane Impurity 7 (CAS 158076-92-7)
- Sevoflurane EP Impurity B (CAS 13171-18-1)
- Sevoflurane EP Impurity A (CAS 58109-34-5)
- Sevoflurane Impurity 5 (CAS 28523-85-5)
- Sevoflurane Impurity 10 (CAS 32793-53-6)
Recommended Standards
- Bis(2,2,2-trifluoroethoxy)methane (CAS 6263-71-4)
- (4-Fluoro-3-(trimethylsilyl)phenyl)boronic acid (CAS 1257792-91-8)
- 8-Bromo-1,2,3,4-tetrahydroquinoline (CAS 937640-02-3)
- 4-methyl-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1440520-87-5)
- Nabumetone Impurity 18 (CAS 701270-26-0)
- Prucalopride Impurity 48 (CAS 137211-63-3)
- Imrecoxib Impurity 23 (CAS CATO-C4X-237923)
- (Z)-5',6'-dichloro-[2,3'-biindolinylidene]-2',3-dione (CAS 667463-72-1)
- (6-Acetamidopyridin-3-yl)boronic acid (CAS 947533-21-3)
- 2-(Benzyloxy)-3,4-difluorobenzoic acid (CAS 2276098-34-9)
- Ethyl 1-(7-methylthieno[3,2-d]pyrimidin-4-yl)piperidine-4-carboxylate (CAS 681428-53-5)
- 4-(Pyridin-2-ylsulfanyl)benzoic acid (CAS 852952-22-8)
- EDTA Sodium trihydrate ferric salt (CAS 18154-32-0)
- Des-Ser39-Tirzepatide (CAS CATO-CPTD788936)
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