2-Iodo-6-methoxypyrazine CAS 58139-03-0
| CAS No. | 58139-03-0 |
| Molecular Formula | C5H5IN2O |
| Molecular Weight | 236.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-Iodo-6-methoxypyrazine (CAS 58139-03-0) is a high-purity analytical reference standard with the molecular formula C5H5IN2O and a molecular weight of 236.01 g/mol.
The molecular framework of 2-Iodo-6-methoxypyrazine (C5H5IN2O) is characterized by an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H5IN2O |
| Molecular Weight | 236.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
Related Iodo Standards
- 5-Iodo-2-methoxypyrimidine (CAS 101803-06-9)
- 5-Iodo-2-methylpyrimidin-4(3H)-one (CAS 111079-41-5)
- 2-(4-Iodo-1H-pyrazol-1-yl)acetaldehyde (CAS 1172074-04-2)
- 4-Iodo-1-methyl-1H-pyrazole-3-carbaldehyde (CAS 1214997-78-0)
- 2-Iodo-5-methoxypyrimidine (CAS 1261783-95-2)
- 5-Iodo-1-methyl-1H-pyrazole-4-carbaldehyde (CAS 1346818-72-1)
- 5-Iodo-2-methylpyridazin-3(2H)-one (CAS 153239-91-9)
- 4-Iodo-6-methoxypyrimidine (CAS 161489-05-0)
Recommended Standards
- 2-Iodo-5-methoxypyrazine (CAS 942624-06-8)
- 2-Iodobenzene-1,3-diol (CAS 41046-67-7)
- 2-Iodo-4-methoxypyrimidine (CAS 262353-35-5)
- 2-iodobenzene-1,4-diol (CAS 23030-43-5)
- 4-Chloro-2-(4-methoxyphenyl)quinazoline (CAS 55391-00-9)
- 3-(Pentafluoroethyl)benzaldehyde (CAS 1450909-97-3)
- 3-Bromo-4-methyl-N-(2,2,2-trifluoroethyl)aniline (CAS 1343245-72-6)
- (S)-4-Chloro-2,3-dihydro-1H-inden-1-amine hydrochloride (CAS 2109874-07-7)
- 10-(4-Bromophenyl)-9(10H)-acridone (CAS 24275-95-4)
- (1-Ethyl-5-methyl-1H-pyrazol-4-yl)methanol (CAS 494214-31-2)
- 3-((2-Hydroxyethoxy)methyl)-6-methyl-3H-imidazo[1,2-a]purin-9(4H)-one (CAS 114199-19-8)
- PF-04217903 (CAS 956905-27-4)
- 3-Formylphenyl 2-chlorobenzoate (CAS 444286-64-0)
- TRAF6 Peptide trifluoroacetate salt (CAS 852805-92-6)
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