Diethyl 2-acetamido-2-((7-chloro-1H-indol-3-yl)methyl)malonate CAS 582319-05-9

Purity 97%+In StockPharmaceutical Standards
CAS No.582319-05-9
Molecular FormulaC18H21ClN2O5
Molecular Weight380.82 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Diethyl 2-acetamido-2-((7-chloro-1H-indol-3-yl)methyl)malonate CAS 582319-05-9 chemical structure

Description

The occurrence of Diethyl 2-acetamido-2-((7-chloro-1H-indol-3-yl)methyl)malonate is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Diethyl 2-acetamido-2-((7-chloro-1H-indol-3-yl)methyl)malonate (CAS 582319-05-9) is a high-purity analytical reference standard with the molecular formula C18H21ClN2O5 and a molecular weight of 380.82 g/mol.

Diethyl 2-acetamido-2-((7-chloro-1H-indol-3-yl)methyl)malonate (C18H21ClN2O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Diethyl 2-acetamido-2-((7-chloro-1H-indol-3-yl)methyl)malonate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H21ClN2O5
Molecular Weight380.82 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Halogen ContentCl-containing
Nitrogen Atoms2

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